Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-118472S

Benazeprilat-d₅
Benazeprilat-d₅ is the deuterium labeled Benazeprilat.

HY-113420S

11-Dehydro-thromboxane B2-d₄		99.9%
11-Dehydro-thromboxane B2-d₄ is the deuterium labeled 11-Dehydro-thromboxane B2.

HY-W031727S

Hydroxychloroquine-d₄-1 sulfate		≥98.0%
Hydroxychloroquine-d₄-1 (sulfate) is the deuterium labeled Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro.

HY-B0006S

Carvedilol-d₃		99.00%
Carvedilol-d₃ is the deuterium labeled Carvedilol. Carvedilol (BM 14190) is a non-selective β/α-1 blocker. Carvedilol inhibits lipid peroxidation in a dose-dependent manner with an IC₅₀ of 5 μM. Carvedilol is a multiple action antihypertensive agent with potential use in angina and congestive heart failure. Carvedilol is an autophagy inducer that inhibits the NLRP3 inflammasome.

HY-B1278S1

α-Tocopherol-d₆ acetate		99.67%
α-Tocopherol-d₆ (acetate) is the deuterium labeled D-α-Tocopherol acetate. D-α-Tocopherol acetate (D-Vitamin E acetate) can be hydrolyzed to d-alpha-tocopherol (VE) and absorbed in the small intestine.

HY-14546S1

Aripiprazole-d₈		99.86%
Aripiprazole (1,1,2,2,3,3,4,4-d₈) is the deuterium labeled Aripiprazole. Aripiprazole (OPC-14597) is a human 5-HT1A receptor partial agonist with a K_i of 4.2 nM.

HY-132641S

Equilin 3-Sulfate-d₄ sodium
Equilin 3-Sulfate-d₄ (sodium) is the deuterium labeled Equilin 3-Sulfate sodium salt.

HY-107494S2

4-Oxoretinoic acid-d₃
4-Oxoretinoic acid-d₃ is the deuterium labeled 4-Oxoretinoic acid.

HY-141749S

(Rac)-Clopidogrel carboxylic acid-d₄		99.51%
(Rac)-Clopidogrel carboxylic acid-d₄ is the deuterium labeled (Rac)-Clopidogrel carboxylic acid.

HY-66008S

N-Acetyl mesalazine-d₃		98.0%
N-Acetyl mesalazine-d₃ (N-Acetyl-5-aminosalicylic acid-d₃) is the deuterium labeled N-Acetyl mesalazine (HY-66008). N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the primary intestinal metabolite of 5-Aminosalicylic Acid (HY-15027) and serves as a biomarker for evaluating the efficacy of 5-Aminosalicylic Acid (HY-15027). N-Acetyl mesalazine can scavenge free radicals, reduce DNA base hydroxylation, and ameliorate mucosal inflammation. N-Acetyl mesalazine can be used in the study of diseases such as colitis and colon cancer.

HY-10873S

N-Desethyl Sunitinib-d₅		99.9%
N-Desethyl Sunitinib-d₅ is the deuterium labeled N-Desethyl Sunitinib. N-Desethyl Sunitinib (SU-12662) is a metabolite of sunitinib. Sunitinib is a potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor with K_i values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively.

HY-G0016S2

N-Acetyl dapsone-d₈		99.47%
N-Acetyl Dapsone-d₈ is the deuterium labeled N-Acetyl Dapsone.

HY-17424S

Penciclovir-d₄
Penciclovir-d₄ is the deuterium labeled Penciclovir. Penciclovir is reported to be potent against HSV types 1 and 2 with IC₅₀ of 0.04-1.8 μg/mL and 0.06-4.4 μg/mL, respectively.

HY-132643S

Benzyldimethyltetradecylammonium-d₇ chloride
Benzyldimethyltetradecylammonium-d₇ (chloride) is the deuterium labeled Benzyldimethyltetradecylammonium chloride.

HY-14249S

Bicalutamide-d₄
Bicalutamide-d₄ is the deuterium labeled Bicalutamide. Bicalutamide is an orally active non-steroidal androgen receptor (AR) antagonist. Bicalutamide can be used for the research of prostate cancer.

HY-17419S1

Ifosfamide-d₄		99.85%
Ifosfamide-d₄ is the deuterium labeled Ifosfamide. Ifosfamide is an alkylating chemotherapeutic agent with activity against a wide range of tumors.

HY-16560S

Camptothecin-d₅		99.61%
Camptothecin-d₅ is the deuterium labeled Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC₅₀ of 679 nM. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells.

HY-132675S

Prochlorperazine Sulfoxide-d₃		99.95%
Prochlorperazine Sulfoxide-d₃ is a deuterium labeled Prochlorperazine Sulfoxide. Prochlorperazine Sulfoxide is the major metabolite of the antiemetic Prochlorperazine.

HY-W009973S

4-Anilino-4-oxobutanoic acid-d₅		99.0%
4-Anilino-4-oxobutanoic acid-d₅ is the deuterium labeled 4-Anilino-4-oxobutanoic acid.

HY-141778S

Retinoic acid ethyl ester-d₅		99.20%
Retinoic acid ethyl ester-d5 is the deuterium labeled Retinoic acid ethyl ester.

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