Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-153939S

Idasanutlin-d₃-1		99.57%
Idasanutlin-d₃-1 (RG7388-d₃-1) is the deuterium labeled Idasanutlin. Idasanutlin is a potent antagonist of MDM2/p53. Idasanutlin inhibits relapsed or refractory acute myeloid leukemia.

HY-133694S

2-Aminoflubendazole-¹³C₆		99.8%
2-Aminoflubendazole-¹³C₆ is the ¹³C₆ labeled 2-Aminoflubendazole. 2-Aminoflubendazole is the metabolite of Benzimidazoles. Benzimidazoles (BZ) are a class of agents with activities against fungi, protozoa, and helminthes.

HY-107322AS1

Barnidipine-d₅		98.97%
Barnidipine-d₅ is the deuterium-labeled Barnidipine (HY-107322A). Barnidipine-d₅ (Mepirodipine) is an L-type calcium antagonist (CaA) with high affinity for [³H] initrendipine binding sites (K_i=0.21 nmol/l), has selective action against CaA receptors. Barnidipine-d₅ (Mepirodipine) is an antihypertensive agent and acts by the reduction of peripheral vascular resistance secondary to its vasodilatory action.

HY-W017049S

Sodium trifluoroacetate-¹³C₂
Sodium trifluoroacetate-¹³C₂ (Trifluoroacetic acid-¹³C₂ sodium) is the ¹³C labeled isotope of Sodium trifluoroacetate.

HY-B0647S1

Butylphthalide-d₃		99.83%
Butylphthalide-d₃ is the deuterium labeled Butylphthalide. Butylphthalide(3-n-Butylphthalide), an anti-cerebral-ischemia agent, is first isolated from the seeds of celery and showes efficacy in animal models of stroke.

HY-17373S

Posaconazole-d₅		99.14%
Posaconazole-d₅ is a deuterium-labeled form of Posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.

HY-W654040

N1-Acetylspermine-d₃ trihydrochloride		99.9%
N1-Acetylspermine-d₃ Trihydrochloride is the deuterium labeled N1-Acetylspermine (HY-113200). N1-Acetylspermine is an endogenous metabolite present in Urine that can be used for the research of Leukemia.

HY-144427S

Vitamin E-¹³C₂,d₆		98.0%
Vitamin E-¹³C₂,d₆ is a ¹³C-labeled and deuterium labeled Vitamin E.

HY-N7123S

Sulfacetamide-d₄		99.04%
Sulfacetamide-d₄ (Sulphacetamide-d₄) is the deuterium labeled Sulfacetamide (HY-N7123). Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic that can be used for the study of ocular infections. Sulfacetamide has antifungal and antibacterial activities.

HY-W768324

Ribitol-¹³C₅		99.9%
Ribitol-¹³C₅ (Adonitol-¹³C₅) is the ¹³C-labeled Ribitol (HY-100582). Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol.

HY-W701532

β-Hyodeoxycholic acid-d₄		99.41%
β-Hyodeoxycholic acid-d₄ (Isohyodeoxycholic acid-d₄) is the deuterium labeled β-Hyodeoxycholic acid.

HY-N7926S

Pentadecane-d₃₂		99.2%
Pentadecane-d₃₂ is the deuterium labeled Pentadecane (HY-N7926). Pentadecane is an orally active natural plant volatile alkane with anti-inflammatory, analgesic, antipyretic and anti-leishmanial activities. Pentadecane presents IC₅₀ values of 65.3 μM, 60.5 μM and 194.8 μM against Leishmania infantum promastigotes, amastigotes and intracellular amastigotes, respectively. Pentadecane downregulates the mRNA expression of TNF-α and IL-12 and inhibits the release of inflammatory mediators. Pentadecane arrests the cell cycle of Leishmania infantum and induces apoptosis. Pentadecane can be applied to the research of inflammation and leishmaniasis.

HY-N15828

Glycochenodeoxycholic acid 3-sulfate-d₄ disodium		99%
Glycochenodeoxycholic acid 3-sulfate-d₄ is the deuterium labeled bile acid.

HY-107349S

Fenoverine-d₈		98.88%
Fenoverine-d₈ is the deuterium labeled Fenoverine. Fenoverine (Spasmopriv) is an orally active and powerful anti-spasmodic drug. Fenoverine reduces calcium ion influx by suppressing voltage dependent calcium channels. Fenoverine has antiemetic, analgesic, and antidiarrheal effects. Fenoverine induces rhabdomyolysis. Fenoverine can be used to study smooth muscle overexcitation related conditions such as gastrointestinal spasms.

HY-W134007S1

Hexadecanoate-¹³C₁₆ potassium		98.40%
Hexadecanoate-¹³C₁₆ (potassium) is the ¹³C-labeled Hexadecanoate sodium. Hexadecanoate potassium can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells.

HY-107372S4

Uridine triphosphate-¹⁵N₂ dilithium		98.0%
Uridine triphosphate-¹⁵N₂ (UTP-¹⁵N₂ dilithium; Uridine 5'-triphosphate-¹⁵N₂) dilithium is ¹⁵N labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.

HY-10882S1

Clotrimazole-d₁₀
Clotrimazole-d₁₀ is deuterated labeled Clotrimazole (HY-10882). Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity.

HY-146929S

18:1 SM (d18:1/18:1)-d₉		≥99.0%
18:1 SM (d18:1/18:1)-d₉ is deuterium labeled 18:1 SM (d18:1/18:1).

HY-103252S2

Monomethyl fumarate-d₂		98.19%
Monomethyl fumarate-d₂ is a deuterium labeled Monomethyl fumarate (HY-103252). Monomethyl fumarate, an active metabolite of Dimethyl fumarate (DMF) (HY-17363), is a potent GPR109A agonist. Monomethyl fumarate has the potential for multiple neuroprotective pathways and other models of retinal disease.

HY-66011AS

Moxifloxacin-d₄		99.9%
Moxifloxacin-d₄ is the deuterium labeled Moxifloxacin. Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.

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