Ribitol-13C5
Based on 1 Customer Validation
Ribitol-13C5 (Adonitol-13C5) is the 13C-labeled Ribitol (HY-100582). Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol.
For research use only. We do not sell to patients.
- Purity: 99.77%
- Formula: 13C5H12O5
- Molecular Weight:157.11
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 488-81-3
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Appearance Solid
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Molecular Weight 157.11
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Formula 13C5H12O5
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Color White to off-white
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SMILES
O[13CH2][13C@@H]([13C@@H]([13C@@H]([13CH2]O)O)O)O
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Synonyms
Adonitol-13C5; Adonite-13C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 50 mg/mL (318.25 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Praissman JL, et al. The functional O-mannose glycan on α-dystroglycan contains a phospho-Ribitol primed for matriglycan addition. Elife. 2016 Apr 29;5. pii: e14473. [Content Brief]
[2]. Toivari MH, et al. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol. Appl Microbiol Biotechnol. 2010 Jan;85(3):731-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.3650 mL | 31.8248 mL | 63.6497 mL | 159.1242 mL |
| 5 mM | 1.2730 mL | 6.3650 mL | 12.7299 mL | 31.8248 mL | |
| 10 mM | 0.6365 mL | 3.1825 mL | 6.3650 mL | 15.9124 mL | |
| 15 mM | 0.4243 mL | 2.1217 mL | 4.2433 mL | 10.6083 mL | |
| 20 mM | 0.3182 mL | 1.5912 mL | 3.1825 mL | 7.9562 mL | |
| 25 mM | 0.2546 mL | 1.2730 mL | 2.5460 mL | 6.3650 mL | |
| 30 mM | 0.2122 mL | 1.0608 mL | 2.1217 mL | 5.3041 mL | |
| 40 mM | 0.1591 mL | 0.7956 mL | 1.5912 mL | 3.9781 mL | |
| 50 mM | 0.1273 mL | 0.6365 mL | 1.2730 mL | 3.1825 mL | |
| 60 mM | 0.1061 mL | 0.5304 mL | 1.0608 mL | 2.6521 mL | |
| 80 mM | 0.0796 mL | 0.3978 mL | 0.7956 mL | 1.9891 mL | |
| 100 mM | 0.0636 mL | 0.3182 mL | 0.6365 mL | 1.5912 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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