2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel
  4. Fenoverine-d8

Fenoverine-d8  (Synonyms: Spasmopriv-d8)

Cat. No.: HY-107349S Purity: 98.88%
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Fenoverine-d8 is the deuterium labeled Fenoverine[1]. Fenoverine (Spasmopriv) is an antispasmodic agent and inhibits calcium channel currents[2]. Fenoverine induces rhabdomyolysis[3].

For research use only. We do not sell to patients.

Fenoverine-d<sub>8</sub> Chemical Structure

Fenoverine-d8 Chemical Structure

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1 mg USD 360 In-stock
5 mg USD 900 In-stock
10 mg USD 1450 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Fenoverine-d8:

Fenoverine-d8 Related Antibodies

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Description

Fenoverine-d8 is the deuterium labeled Fenoverine[1]. Fenoverine (Spasmopriv) is an antispasmodic agent and inhibits calcium channel currents[2]. Fenoverine induces rhabdomyolysis[3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fenoverine-d8 Related Antibodies
Molecular Weight

467.61

Formula

C26H17D8N3O3S
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1C2=C(C=CC=C2)SC3=CC=CC=C13)CN4C([2H])([2H])C([2H])([2H])N(CC5=CC=C(OCO6)C6=C5)C([2H])([2H])C4([2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (213.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1385 mL 10.6927 mL 21.3853 mL
5 mM 0.4277 mL 2.1385 mL 4.2771 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1385 mL 10.6927 mL 21.3853 mL 53.4634 mL
5 mM 0.4277 mL 2.1385 mL 4.2771 mL 10.6927 mL
10 mM 0.2139 mL 1.0693 mL 2.1385 mL 5.3463 mL
15 mM 0.1426 mL 0.7128 mL 1.4257 mL 3.5642 mL
20 mM 0.1069 mL 0.5346 mL 1.0693 mL 2.6732 mL
25 mM 0.0855 mL 0.4277 mL 0.8554 mL 2.1385 mL
30 mM 0.0713 mL 0.3564 mL 0.7128 mL 1.7821 mL
40 mM 0.0535 mL 0.2673 mL 0.5346 mL 1.3366 mL
50 mM 0.0428 mL 0.2139 mL 0.4277 mL 1.0693 mL
60 mM 0.0356 mL 0.1782 mL 0.3564 mL 0.8911 mL
80 mM 0.0267 mL 0.1337 mL 0.2673 mL 0.6683 mL
100 mM 0.0214 mL 0.1069 mL 0.2139 mL 0.5346 mL
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Fenoverine-d8 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fenoverine-d8Spasmopriv-d8Calcium ChannelCa2+ channelsCa channelsInhibitorinhibitorinhibit

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