Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W266188

Decanoic acid-¹³C		98.0%
Decanoic acid-¹³C is the ¹³C-labeled Decanoic acid (HY-W015309). Decanoic acid is a key component of the medium-chain triglyceride (MCT) found in coconut oil. Decanoic acid is a brain-penetrant and non-competitive inhibitor of AMPA receptor showing antiseizure activity in rats. Decanoic acid reduces tyrosinase activity and inhibits melanosome maturation. Decanoic acid suppresses the phosphorylation of c-Met and induced apoptosis in hepatocellular carcinoma (HCC) cells by inhibiting the expression of various oncogenic proteins, which is promising for research in the field of mTORC1 signaling, HCC and epilepsy.

HY-10569S1

Ponesimod-d₇
Ponesimod-d₇ (ACT-128800-d₇) is the deuterium-labeled Ponesimod (HY-10569). Ponesimod-d₇ (ACT-128800) is a potent, selective and orally active agonist of S1P₁, with an IC₅₀ of 6 nM in a radioligand binding assay. Ponesimod-d₇ activates S1P₁-mediated signal transduction with high potency (EC₅₀=5.7 nM). Ponesimod-d₇ can protect against lymphocyte-mediated tissue inflammation.

HY-B1836S

Meldonium-d₃
Meldonium-d3 is the deuterated form of Meldonium. Meldonium is a cardiovascular protective agent that competitively inhibits BBOX1 and OCTN2. The IC₅₀ value of Mildronate against human recombinant BBOX is 34-62 μM, and the EC₅₀ value against human OCTN2 is 21 μM. Meldonium is a fatty acid oxidation inhibitor.

HY-158086S

N-(1-Oxotridecyl)glycine-d₂
N-(1-Oxotridecyl)glycine-d₂ is the deuterated labeled N-(1-Oxotridecyl)glycine.

HY-U00050S

(E)-10-Hydroxynortriptyline-d₃		99.65%
(E)-10-Hydroxynortriptyline-d₃ is a deuterium labeled (E)-10-Hydroxy Nortriptyline. (E)-10-Hydroxy Nortriptyline is a metabolite of Nortriptyline. Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression.

HY-146796S

15:0 Cholesteryl ester-d₇		99.9%
15:0 Cholesteryl ester-d₇ is deuterium labeled 15:0 Cholesteryl ester.

HY-W654105

C18-Ceramide-¹³C₂,d₂
C18-Ceramide-13C2,d2 is a deuterated labeled C18-Ceramide-13C2,d2.

HY-W004292S

1-Undecanol-d₂₃		98.2%
1-Undecanol-d₂₃ (Undecyl alcohol-d₂₃) is the deuterium labeled 1-Undecanol (HY-W004292). 1-Undecanol (Undecyl alcohol) is the main product generated from the degradation of 2-tridecanone by Pseudomonas bacteria isolated from the soil. 1-Undecanol can enhance the attraction of Grapholita molesta to sex pheromone traps.

HY-133685S

N-Hexanoyl-L-homoserine lactone-d₃		98.2%
N-Hexanoyl-L-Homoserine lactone-d₃ (C6-HSL-d₃) is deuterium labeled N-Hexanoyl-L-homoserine lactone. N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). Diatoms are frequently found in association with Proteobacteria, many members of which employ cell-to-cell communication via AHLs in aquatic habitats.

HY-152006S

Propionyl-L-carnitine-d₃ hydrochloride		99.9%
Propionyl-L-carnitine-d₃ (hydrochloride) is deuterium labeled Propionyl-L-carnitine. Propionyl-L-carnitine is a carnitine derivative and has a high affinity for muscular carnitine transferase. Propionyl-L-carnitine increases cellular carnitine content, thereby allowing free fatty acid transport into the mitochondria. Propionyl-L-carnitine alleviates the symptoms of PAD through a metabolic pathway, thereby improving exercise performance.

HY-101400S

Deoxycytidine triphosphate-d₁₄ dilithium
Deoxycytidine triphosphate-d₁₄ (dCTP-d₁₄ dilithium; 2′-Deoxycytidine-5′-triphosphate-d₁₄) dilithium is deuterium labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-132960S

N-Propionylglycine-2,2-d₂
N-Propionylglycine-2,2-d₂ is the deuterium labeled N-Propionylglycine-2,2.

HY-146798S

1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine-d₇		99%
1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine-d₇ is deuterium labeled 1-Pentadecanoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine.

HY-111772S

Elexacaftor-¹³C,d₃
Elexacaftor-¹³C,d₃ is the deuterium labeled Elexacaftor (HY-111772).

HY-Y0308S

Phosphate dibasic-d₁ sodium		99.0%
Phosphate dibasic-d₂ (sodium) is the deuterium labeled Sodium phosphate dibasic.

HY-111372S1

Finerenone-d₅
Finerenone-d₅ (BAY 94-8862-d₅) is deuterium labeled Finerenone. Finerenone (BAY 94-8862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC₅₀=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.

HY-B0615AS

Moricizine-d₈ Hydrochloride		99.61%
Moricizine-d₈ Hydrochloride is the deuterium labeled Moricizine Hydrochloride (HY-B0615A). Moricizine Hydrochloride is an orally active Class I antiarrhythmic agent. Moricizine Hydrochloride decreases the maximum rate of phase 0 depolarization; increases rates of phase 2 and 3 repolarization, decreases action potential duration, and decreases effective refractory period.

HY-B0843AS

Metalaxyl-M-d₆		99.9%
Metalaxyl-M-d₆ ((R)-Metalaxyl-d₆) is the deuterium labeled Metalaxyl-M (HY-B0843A). Metalaxyl-M ((R)-Metalaxyl) is an orally active and selective inhibitor of fungal RNA polymerase, which exerts fungicidal activity by selectively interfering with the synthesis of fungal ribosomal RNA. Metalaxyl-M can also be used to induce inflammation in hepatocytes and regulate tryptophan metabolism. Metalaxyl-M can be used in ecotoxicology studies.

HY-W714767

Octisalate-d₄
Octisalate-d₄ (Octyl salicylate-d₄; 2-Ethylhexyl salicylate-d₄) is the deuterium labeled Octisalate (HY-B0929). Octisalate (Octyl salicylate) is an organic compound with high lipophilicity, which is used in sunscreens and cosmetics that absorbs UVB rays.

HY-130691S

MitoP-d₁₅ bromide
MitoP-d₁₅ (bromide) is the deuterium labeled MitoP bromide.

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