N-Hexanoyl-L-homoserine lactone-d3
Based on 1 Customer Validation
N-Hexanoyl-L-Homoserine lactone-d3 (C6-HSL-d3) is deuterium labeled N-Hexanoyl-L-homoserine lactone. N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). Diatoms are frequently found in association with Proteobacteria, many members of which employ cell-to-cell communication via AHLs in aquatic habitats.
For research use only. We do not sell to patients.
- Purity: 98.2%
- CAS No.: 2705226-73-7
- Formula: C10H14D3NO3
- Molecular Weight:202.27
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2705226-73-7
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Unlabeled Cas 147852-83-3
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Appearance Solid
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Molecular Weight 202.27
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Formula C10H14D3NO3
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Color White to off-white
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SMILES
O=C1[C@H](CCO1)NC(CCCCC([2H])([2H])[2H])=O
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Synonyms
C6-HSL-d3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 30 mg/mL (148.32 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Frederike Stock,et al. Distinctive Growth and Transcriptional Changes of the Diatom Seminavis robusta in Response to Quorum Sensing Related Compounds. Front Microbiol. 2020 Jun 9;11:1240. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.9439 mL | 24.7194 mL | 49.4389 mL | 123.5972 mL |
| 5 mM | 0.9888 mL | 4.9439 mL | 9.8878 mL | 24.7194 mL | |
| 10 mM | 0.4944 mL | 2.4719 mL | 4.9439 mL | 12.3597 mL | |
| 15 mM | 0.3296 mL | 1.6480 mL | 3.2959 mL | 8.2398 mL | |
| 20 mM | 0.2472 mL | 1.2360 mL | 2.4719 mL | 6.1799 mL | |
| 25 mM | 0.1978 mL | 0.9888 mL | 1.9776 mL | 4.9439 mL | |
| 30 mM | 0.1648 mL | 0.8240 mL | 1.6480 mL | 4.1199 mL | |
| 40 mM | 0.1236 mL | 0.6180 mL | 1.2360 mL | 3.0899 mL | |
| 50 mM | 0.0989 mL | 0.4944 mL | 0.9888 mL | 2.4719 mL | |
| 60 mM | 0.0824 mL | 0.4120 mL | 0.8240 mL | 2.0600 mL | |
| 80 mM | 0.0618 mL | 0.3090 mL | 0.6180 mL | 1.5450 mL | |
| 100 mM | 0.0494 mL | 0.2472 mL | 0.4944 mL | 1.2360 mL |
N-Hexanoyl-L-homoserine lactone-d3 Related Classifications
HY-133685S Related Classifications
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