2. Signaling Pathways
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  4. Reference Standards

Reference Standards

Material, sufficiently homogeneous and stable with respect to one or more specified properties, and the uses include the calibration of a measurement system, assessment of a measurement procedure, assigning values to other materials, and quality control and so on.

Reference Standards Related Products (10971):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N2070R
    Acevaltrate (Standard)
    Acevaltrate inhibits the Na+/K+-ATPase activity in the rat kidney and brain hemispheres with IC50s of 22.8 μM and 42.3 μM, respectively.
    Acevaltrate (Standard)
  • HY-107505AR
    CBiPES (Standard)
    CBiPES (Standard) is the analytical standard of CBiPES (HY-107505A). This product is intended for research and analytical applications. CBiPES is a potent mGlu2 positive allosteric modulator with an EC50 value of 92.8 nM. CBiPES attenuates stress-induced hyperthermia and Phencyclidine-induced hyperlocomotor activity. CBiPES can be used for research of neurological diseases, such as ParKinson's disease (PD).
    CBiPES (Standard)
  • HY-13511R
    Rupatadine (Standard)
    Rupatadine (Standard) is the analytical standard of Rupatadine. This product is intended for research and analytical applications. Rupatadine (UR-12592) is a potent, orally active and long-lasting dual PAF/H1 antagonist, with Kis of 0.55 μM and 0.1 μM, respectively. Rupatadine can be used for the research of allergic rhinitis and urticaria.
    Rupatadine (Standard)
  • HY-10349R
    WAY-100635 (Standard)
    WAY-100635 (Standard) is the analytical standard of WAY-100635. This product is intended for research and analytical applications. WAY-100635 is a potent and selective 5-HT1A Receptor antagonist with a pIC50 of 8.87, an apparent pA2 of 9.71. WAY-100635 is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 value of 0.91 nM and Ki value of 0.39 nM. WAY-100635 has pIC50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 is also a potent dopamine D4 receptor agonist.
    WAY-100635 (Standard)
  • HY-N8259R
    Obovatol (Standard)
    Obovatol (Standard) is the analytical standard of Obovatol (HY-N8259). This product is intended for research and analytical applications. Obovatol is a biphenyl ether lignan isolated from the leaves of Magnolia obovata Thunb.
    Obovatol (Standard)
  • HY-13338R
    Mabuterol (Standard)
    Mabuterol (Standard) is the analytical standard of Mabuterol. This product is intended for research and analytical applications. Mabuterol is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB.
    Mabuterol (Standard)
  • HY-Z3770R
    Enzalutamide impurity 4 (Standard)
    methyl 2-fluoro-4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate (Enzalutamide Impurity） (Standard) is the analytical standard of methyl 2-fluoro-4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate (Enzalutamide Impurity）. This product is intended for research and analytical applications.
    Enzalutamide impurity 4 (Standard)
  • HY-B0338R
    Rimantadine (Standard)
    Rimantadine (Standard) is the analytical standard of Rimantadine. This product is intended for research and analytical applications. Rimantadine is an orally active inhibitor for M2 protein, that blocks the hydrogen ion channel activity, prevents the entry and replication of the virus, and exhibits board-spectrum antiviral activity.
    Rimantadine (Standard)
  • HY-13599R
    Cladribine (Standard)
    Cladribine (Standard) is the analytical standard of Cladribine. This product is intended for research and analytical applications. Cladribine (2-Chloro-2′-deoxyadenosine), a purine nucleoside analog, is an orally active adenosine deaminase inhibitor. Cladribine functions as an inhibitor of DNA synthesis to block the repair of the damaged DNA. Cladribine can inhibit DNA methylation. Cladribine has anti-lymphoma activity. Cladribine can be used for the research of several hematologic malignancies and multiple sclerosis.
    Cladribine (Standard)
  • HY-N6063R
    (+)-Peusedanol (Standard)
    (+)-Peusedanol (Standard) is the analytical standard of (+)-Peusedanol. This product is intended for research and analytical applications. (+)-Peusedanol is a coumarin isolated from Peucedanumjaponicum.
    (+)-Peusedanol (Standard)
  • HY-100588AR
    VU0364770 hydrochloride (Standard)
    VU0364770 (hydrochloride) (Standard) is the analytical standard of VU0364770 (hydrochloride) (HY-100588A). This product is intended for research and analytical applications. VU0364770 hydrochloride is a selective and potent positive allosteric modulator (PAM) of mGlu4. VU0346770 hydrochloride exhibits EC50s of 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor, respectively. VU0364770 hydrochloride exhibits antagonist activity at mGlu5 with a potency of 17.9 μM and PAM activity at mGlu6 with a potency of 6.8 μM. VU0364770 hydrochloride also possesses activity at MAO with Ki values of 8.5 and 0.72 μM for human MAO-A and human MAO-B, respectively.
    VU0364770 hydrochloride (Standard)
  • HY-100373R
    Isavuconazonium sulfate (Standard)
    Isavuconazonium (sulfate) (Standard) is the analytical standard of Isavuconazonium (sulfate) (HY-100373). This product is intended for research and analytical applications. Isavuconazonium sulfate (BAL8557-002) is an orally active broad-spectrum antifungal molecule. Isavuconazonium sulfate is a precursor of the triazole antifungal active molecule Isavuconazole. Isavuconazonium sulfate can be used in the study of invasive aspergillosis, mucormycosis, blastomycosis, and Acanthamoeba keratitis.
    Isavuconazonium sulfate (Standard)
  • HY-103603AR
    (S,R,S)-AHPC-PEG2-NH2 (Standard)
    (S,R,S)-AHPC-PEG2-NH2 (Standard) is the analytical standard of (S,R,S)-AHPC-PEG2-NH2 (HY-103603A). This product is intended for research and analytical applications. (S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs.
    (S,R,S)-AHPC-PEG2-NH2 (Standard)
  • HY-131114R
    Valiolamine (Standard)
    Valiolamine (Standard) is the analytical standard of Valiolamine (HY-13114). This product is intended for research and analytical applications. Valiolamine, an aminocyclitol, is an alpha-glucosidase inhibitor. Valiolamine has potent alpha-glucosidase inhibitory activity against porcine intestinal sucrase, maltase and isomaltase. Valiolamine binds to porcine intestinal maltase and sucrase with Ki values of 350 nM and 30 nM, respectively.
    Valiolamine (Standard)
  • HY-113373R
    Guanidinosuccinic acid (Standard)
    Guanidinosuccinic acid (Standard) is the analytical standard of Guanidinosuccinic acid. This product is intended for research and analytical applications. Guanidinosuccinic acid is a nitrogenous metabolite.
    Guanidinosuccinic acid (Standard)
  • HY-W009051R
    Decamethylcyclopentasiloxane (Standard)
    Decamethylcyclopentasiloxane (Standard) is the analytical standard of Decamethylcyclopentasiloxane. This product is intended for research and analytical applications. Decamethylcyclopentasiloxane (D5), an organosilicon compound that is used as a skin emollient in cosmetics and personal products.
    Decamethylcyclopentasiloxane (Standard)
  • HY-103078R
    I-XW-053 (Standard)
    I-XW-053 (Standard) is the analytical standard of I-XW-053 (HY-103078). This product is intended for research and analytical applications. I-XW-053 is a specific anti-HIV-1 capsid inhibitor (IC50=164.2 μM). By binding to the CA NTD-NTD hexamerization interface and the R173 region of CTD (Kd=66.3 μM), I-XW-053 disrupts capsid function and reduces polymerization levels. I-XW-053 effectively blocks HIV-1 uncoating, inhibits reverse transcription and early replication, and exhibits broad-spectrum activity against primary HIV-1 isolates in peripheral blood mononuclear cells. I-XW-053 can be widely used in studies related to HIV-1 infection.
    I-XW-053 (Standard)
  • HY-103566R
    LY456236 (Standard)
    LY456236 (Standard) is the analytical standard of LY456236 (HY-103566). This product is intended for research and analytical applications. LY456236 is a selective, non-competitive and orally active antagonist of glutamate receptor 1 (mGlu1), which can inhibit phosphatidylinositol hydrolysis with an IC50 of 0.145 μM. LY456236 can also inhibit EGFR, with an IC50 of 0.918 μM. LY456236 has anticonvulsant effects and blocks cell proliferation by inhibiting the MAPK pathway, reversing the anti-apoptotic effect of DHPG (HY-12598A). LY456236 can be used in epilepsy research.
    LY456236 (Standard)
  • HY-10900R
    TCS 1102 (Standard)
    TCS 1102 (Standard) is the analytical standard of TCS 1102 (HY-10900). This product is intended for research and analytical applications. TCS 1102 is a potent, dual orexin receptor antagonist, with Ki values of 0.2 nM and 3 nM for OX2 and OX1 receptors, respectively. TCS 1102 demonstrates excellent blood-brain barrier penetrability and moderate bioavailability in rats.
    TCS 1102 (Standard)
  • HY-W104249R
    N,N-1,3-Phenylenedimaleimide (Standard)
    N,N-1,3-Phenylenedimaleimide (Standard) is the analytical standard of N,N-1,3-Phenylenedimaleimide. This product is intended for research and analytical applications.
    N,N-1,3-Phenylenedimaleimide (Standard)