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Cat. No.: HY-100373R

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Isavuconazonium sulfate (Standard)

(Synonyms: BAL8557-002 (Standard))

Isavuconazonium (sulfate) (Standard) is the analytical standard of Isavuconazonium (sulfate) (HY-100373). This product is intended for research and analytical applications. Isavuconazonium sulfate (BAL8557-002) is an orally active broad-spectrum antifungal molecule. Isavuconazonium sulfate is a precursor of the triazole antifungal active molecule Isavuconazole. Isavuconazonium sulfate can be used in the study of invasive aspergillosis, mucormycosis, blastomycosis, and Acanthamoeba keratitis.

For research use only. We do not sell to patients.

Purity: 95%
CAS No.: 946075-13-4
Formula: C₃₅H₃₆F₂N₈O₉S₂
Molecular Weight:814.84

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Isavuconazonium sulfate (Standard) Chemical Structure

CAS No.: 946075-13-4

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Product Information
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- Application
Chemical Information
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 946075-13-4
Molecular Weight 814.84
Formula C₃₅H₃₆F₂N₈O₉S₂
SMILES

O[C@@](CN(N=C1)C=[N+]1C(C)OC(N(C(N=CC=C2)=C2COC(CNC)=O)C)=O)(C(C=C3F)=C(C=C3)F)[C@H](C4=NC(C(C=C5)=CC=C5C#N)=CS4)C.O=[S]([O-])(O)=O
Synonyms

BAL8557-002 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Kovanda L L, et al. Isavuconazonium sulfate: a new agent for the treatment of invasive aspergillosis and invasive mucormycosis[J]. Expert review of clinical pharmacology, 2016, 9(7): 887-897.

[2]. Shing B, et al. Evaluation of Amebicidal and Cysticidal Activities of Antifungal Drug Isavuconazonium Sulfate against Acanthamoeba T4 Strains. Pharmaceuticals (Basel). 2021 Dec 11;14(12):1294. [Content Brief]

[3]. Slain D, et al. Isavuconazonium sulfate: a novel antifungal agent[J]. Current Fungal Infection Reports, 2015, 9: 302-313.

[4]. Luo G, et al. Isavuconazole therapy protects immunosuppressed mice from mucormycosis[J]. Antimicrobial agents and chemotherapy, 2014, 58(4): 2450-2453.

[5]. Scolarici MJ, et al. The Role of Isavuconazonium Sulphate for the Treatment of Blastomycosis: A Case Series and Antifungal Susceptibility. Open Forum Infect Dis. 2022 Apr 27;9(7):ofac220. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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