2. Signaling Pathways
  3. Epigenetics
  4. Small Interfering RNA (siRNA)

Small Interfering RNA (siRNA)

Small Interfering RNA (siRNA) is a small exogenous double-stranded RNA (dsRNA) (20-25 nucleotides), which triggers the RNA interference (RNAi) pathway. The short dsRNA unwinds and the sense strand is degraded. Antisense strand forms RNA induced silencing complex (RISC) with various protein components. The antisense strand retained in RISC is specifically complementary to the target gene mRNA. Meanwhile, RISC has nuclease activity, which can cut and degrade the target gene mRNA, and inhibit the expression of target gene. Incomplete complementarity results in mRNA translation inhibition.

Small Interfering RNA (siRNA) Related Products (29582):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-RS16526
    Trem2 Mouse Pre-designed siRNA Set A
    		Pre-designed Set

    Trem2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trem2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Trem2 Mouse Pre-designed siRNA Set A
  • HY-RS15912
    Yap1 Mouse Pre-designed siRNA Set A
    		Pre-designed Set

    Yap1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Yap1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Yap1 Mouse Pre-designed siRNA Set A
  • HY-RS17539
    Klf2 Mouse Pre-designed siRNA Set A
    		Pre-designed Set

    Klf2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Klf2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Klf2 Mouse Pre-designed siRNA Set A
  • HY-RS07015
    JAK1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    JAK1 Human Pre-designed siRNA Set A contains three designed siRNAs for JAK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    JAK1 Human Pre-designed siRNA Set A
  • HY-RS02248
    CD44 Human Pre-designed siRNA Set A
    		Pre-designed Set

    CD44 Human Pre-designed siRNA Set A contains three designed siRNAs for CD44 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    CD44 Human Pre-designed siRNA Set A
  • HY-RS00136
    ACAT1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    ACAT1 Human Pre-designed siRNA Set A contains three designed siRNAs for ACAT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    ACAT1 Human Pre-designed siRNA Set A
  • HY-RS04406
    Ep300 Mouse Pre-designed siRNA Set A
    		Pre-designed Set

    Ep300 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ep300 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Ep300 Mouse Pre-designed siRNA Set A
  • HY-RS15321
    UBA3 Human Pre-designed siRNA Set A
    		Pre-designed Set

    UBA3 Human Pre-designed siRNA Set A contains three designed siRNAs for UBA3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    UBA3 Human Pre-designed siRNA Set A
  • HY-RS15355
    UBE2M Human Pre-designed siRNA Set A
    		Pre-designed Set

    UBE2M Human Pre-designed siRNA Set A contains three designed siRNAs for UBE2M gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    UBE2M Human Pre-designed siRNA Set A
  • HY-RS29497
    GAL3ST2 Human Pre-designed siRNA Set A
    		Pre-designed Set
    GAL3ST2 Human Pre-designed siRNA Set A contains three designed siRNAs for GAL3ST2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Components
    GAL3ST2 siRNA-1: 5 nmol (HPLC)
    GAL3ST2 siRNA-2: 5 nmol (HPLC)
    GAL3ST2 siRNA-3: 5 nmol (HPLC)
    siRNA Negative Control: 5 nmol (HPLC)
    FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
    GAPDH siRNA Positive Control: 5 nmol (HPLC)
    GAL3ST2 Human Pre-designed siRNA Set A
  • HY-RS29488
    Or5m3b Mouse Pre-designed siRNA Set A
    		Pre-designed Set
    Or5m3b Mouse Pre-designed siRNA Set A includes three pairs of siRNAs designed for different regions of the Or5m3b (Mouse) gene, as well as a negative control, a FAM-labeled negative control, and a positive control.
    Or5m3b Mouse Pre-designed siRNA Set A
  • HY-RS01682
    BUB1B Human Pre-designed siRNA Set A
    		Pre-designed Set

    BUB1B Human Pre-designed siRNA Set A contains three designed siRNAs for BUB1B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    BUB1B Human Pre-designed siRNA Set A
  • HY-RS11116
    PRKCA Human Pre-designed siRNA Set A
    		Pre-designed Set

    PRKCA Human Pre-designed siRNA Set A contains three designed siRNAs for PRKCA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    PRKCA Human Pre-designed siRNA Set A
  • HY-RS03730
    DHFR Human Pre-designed siRNA Set A
    		Pre-designed Set

    DHFR Human Pre-designed siRNA Set A contains three designed siRNAs for DHFR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    DHFR Human Pre-designed siRNA Set A
  • HY-RS16309
    Rab27a Mouse Pre-designed siRNA Set A
    		Pre-designed Set

    Rab27a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Rab27a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Rab27a Mouse Pre-designed siRNA Set A
  • HY-147425
    Zerlasiran
    Zerlasiran (SLN360) is a siRNA targeting apolipoprotein A (ApoA). Zerlasiran targets hepatic ApoA synthesis via RNA interference to degrade encoding mRNA. Zerlasiran can be used for the research of atherosclerotic cardiovascular disease and elevated ApoA levels.
    Zerlasiran
  • HY-164221A
    Rapirosiran sodium
    Rapirosiran (ALN-HSD) sodium is a HSD17β13-targeting siRNA. Rapirosiran sodium can be used for the research of metabolic dysfunction-associated steatohepatitis.
    Rapirosiran sodium
  • HY-132606
    Nedosiran
    Nedosiran (DCR-PHXC) is an RNA interference (RNAi) targeting lactate dehydrogenase (LDH). Nedosiran represents an impactful potential therapeutic for primary hyperoxaluria (PH) with end-stage renal disease (ESRD). Nedosiran is a GalNAc-dsRNA conjugate.
    Nedosiran
  • HY-RS01170
    ATOX1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    ATOX1 Human Pre-designed siRNA Set A contains three designed siRNAs for ATOX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    ATOX1 Human Pre-designed siRNA Set A
  • HY-RS04713
    FAM3C Human Pre-designed siRNA Set A
    		Pre-designed Set

    FAM3C Human Pre-designed siRNA Set A contains three designed siRNAs for FAM3C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    FAM3C Human Pre-designed siRNA Set A