Rapirosiran sodium
Based on 1 Customer Validation
Rapirosiran (ALN-HSD) sodium is a HSD17β13-targeting siRNA. Rapirosiran sodium can be used for the research of metabolic dysfunction-associated steatohepatitis.
For research use only. We do not sell to patients.
- Purity : 97.39%
- CAS No.: 2755197-77-2
- Molecular Weight:16307.22 (free acid)
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All 17β-HSD Isoforms
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Biological Activity
Description
In Vitro
Rapirosiran sodium can silence HSD17β13 in the liver, thereby reducing free fatty acid levels[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 2755197-77-2
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Appearance Solid
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Molecular Weight 16307.22 (free acid)
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Color White to off-white
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SMILES
[Rapirosiran (sodium)]
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Synonyms
ALN-HSD sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Protocols
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RNA interference technology
RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing gene transcription or activating RNA degradation. This mechanism was discovered in plants in 1998 by Andrew Fire and Craig Mello. Today, this phenomenon can be observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals.
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2242 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)