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Tariquidar

(Synonyms: XR9576)
57 Cited Publications
고객리뷰

Based on 57 publication(s) in Google Scholar

Tariquidar (XR9576) is a potent and specific inhibitor of P-glycoprotein (P-gp) with the high affinity (Kd=5.1 nM).

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

  • Purity: 99.45%
  • CAS No.: 206873-63-4
  • 화학식: C38H38N4O6
  • 분자량:646.73
  • 보관:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 2 years , -20°C, 1 year
  • Tariquidar Chemical Structure
    Tariquidar Chemical Structure
  • Experimental Validation Results for Tariquidar
  • Experimental Validation Results for Tariquidar
  • Experimental Validation Results for Tariquidar
  • Experimental Validation Results for Tariquidar
  • Experimental Validation Results for Tariquidar
CAS No.: 206873-63-4
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In Vivo Efficacy StudyCell Proliferation/Viability AssayWBCell Imaging/StainingFlow Cytometry
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  • Tariquidar Chemical Structure
    Tariquidar Chemical Structure
    1/16
  • 1/16

    Tariquidar purchased from MedChemExpress. Usage Cited in: Cell. 2023 Dec 7;186(25):5500-5516.e21. [Abstract]

    Customer Validation
     Survival curves of mice under SD (SR means 48 h of recovery after SD) with i.p. administration of tariquidar (n = 5) or vehicle (n = 5).

  • 1/16

    Tariquidar purchased from MedChemExpress. Usage Cited in: Cell Death Discov. 2021 Aug 5;7(1):204. [Abstract]

    Customer Validation
     MCF-7ADR cells were treated with ADR (2μM) alone or together with Tariquidar (TQ; 0.5 μM) for 48h. Cell viability was detected using the CCK8 assays.

  • 1/16

    Tariquidar purchased from MedChemExpress. Usage Cited in: Antioxidants (Basel). 2021 Jun 11;10(6):949. [Abstract]

    Customer Validation
     Tariquidar (1.5 μM; 72 h). Western blotting results show the specific inhibition of both MRP1/ABCC1 and MDR1/ABCB1 after tariquidar treatment for 72 h in both control and DEHP-exposed MDA-MB-231 clones.

  • 1/16

    Tariquidar purchased from MedChemExpress. Usage Cited in: Antioxidants (Basel). 2021 Jun 11;10(6):949. [Abstract]

    Customer Validation
     Tariquidar (1.5 μM; 2 h). Enhanced Dox accumulation was observed following 2 h of Tariquidar pretreatment in DEHP-exposed MDA-MB-231 clones #1 and #2, analyzed by a BD Accuri TW C6 flow cytometer.

  • 1/16

    Tariquidar purchased from MedChemExpress. Usage Cited in: Small. 2020 Nov;16(44):e2004172. [Abstract]

    Customer Validation
     In vitro tumor penetration of the DOX-loaded liposomes in BxPC3 MTS. The BxPC3 MTS were prestained with or without a Pg-p inhibitor Tariquidar (10 nM) for 3 h. Subsequently, the MTS were cultured with DOX-loaded liposomes for 6 h. The MTS were visualized using CLSM in Z-stacks with 25 µm intervals. DOX (red).

  • Tariquidar