δ-Sleep Inducing Peptide (Synonyms: Delta-Sleep Inducing Peptide)

Name: δ-Sleep Inducing Peptide
Brand: MedChemExpress
SKU: HY-P1501
Rating: 4.5 (0 reviews)

Cat. No.: HY-P1501 Pureza: 99.95%: Ficha de datos
COA

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Instrucciones de manejo
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δ-Sleep Inducing Peptide is a neuropeptide, with antioxidant and anxiolytic properties.

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Síntesis de péptidos personalizados

δ-Sleep Inducing Peptide Estructura química

No. CAS : 62568-57-4

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5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
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Based on 1 Customer Validation

Other Forms of δ-Sleep Inducing Peptide:

δ-Sleep Inducing Peptide acetate In-stock

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Descripciòn

δ-Sleep Inducing Peptide is a neuropeptide, with antioxidant and anxiolytic properties.

In Vivo

δ-Sleep Inducing Peptide (DSIP) increases the spindle activity increased in rabbit in vivo, and decreases heart and respiration rate as well. δ-Sleep Inducing Peptide (DSIP) may act as a programming modulator at supra-operational level rather than as a transmitter at operational level^[1]. δ-Sleep Inducing Peptide (DSIP; 40-360 μg/kg, i.p.) increases catalase and superoxide dismutase (SOD) activities and malonic dialdehyde (MDA) concentration in 40 μg/kg in the liver homogenate of rats subjected to acute stress, but exhibits the opposite effects at 120 μg/kg, and 360 μg/kg^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

848.81

Fòrmula

C₃₅H₄₈N₁₀O₁₅

No. CAS

62568-57-4

Appearance

Solid

Color

White to light yellow

Sequence

Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

Sequence Shortening

WAGGDASGE

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad

In Vitro:

H₂O

Peptide Solubility and Storage Guidelines:

1. Calculate the length of the peptide.

2. Calculate the overall charge of the entire peptide according to the following table:

	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3. Recommended solution:

Overall charge of peptide	Details
Negative (<0)	1. Try to dissolve the peptide in water first. 2. If water fails, add NH₄OH (<50 μL). 3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0)	1. Try to dissolve the peptide in water first. 2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

Pureza y Documentación

Purity: 99.95%

Select Batch:

Ficha de datos (263 KB) SDS (254 KB)

COA (245 KB) LCMS (101 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Monnier M, et al. The delta sleep inducing peptide (DSIP). Comparative properties of the original and synthetic nonapeptide. Experientia. 1977 Apr 15;33(4):548-52. [Content Brief]

[2]. Bobyntsev II, et al. Effect of Delta Sleep-Inducing Peptide on Functional State of Hepatocytes in Rats During Restraint Stress. Bull Exp Biol Med. 2016 Feb;160(4):421-4. [Content Brief]

Administraciòn de animales
^[2]

Rats^[2]
Experiments are performed on male Wistar rats (n = 100) weighing 250-280 g. The animals are divided into groups (10 specimens per group). They are maintained under standard vivarium conditions and have free access to water and food (12:12-h light/dark regimen). δ-Sleep Inducing Peptide is dissolved in physiological saline and injected intraperitoneally 60 min before each stress exposure. Control animals receive an equivalent volume of physiological saline (1 mL/kg). The liver is homogenized in ice-cold physiological saline and centrifuged. The content of LPO products and activities of antioxidant enzymes are measured in the supernatant. LPO intensity is evaluated by malonic dialdehyde (MDA) concentration. Activities of superoxide dismutase (SOD) and catalase are measured spectrophotometrically. The total antioxidant activity (TAA) is evaluated by the method based on inhibition of ascorbate-induced and iron-induced oxidation of Tween-80 to MDA. The assay is conducted on a BTS-330 biochemical analyzer^[2].

MCE no ha confirmado la precisión de estos métodos independientemente. Son solo para referencia.

Referencias

[1]. Monnier M, et al. The delta sleep inducing peptide (DSIP). Comparative properties of the original and synthetic nonapeptide. Experientia. 1977 Apr 15;33(4):548-52. [Content Brief]

[2]. Bobyntsev II, et al. Effect of Delta Sleep-Inducing Peptide on Functional State of Hepatocytes in Rats During Restraint Stress. Bull Exp Biol Med. 2016 Feb;160(4):421-4. [Content Brief]

δ-Sleep Inducing Peptide Related Classifications

Neurological Disease

Calculadora de molaridad
Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

δ-Sleep Inducing Peptide62568-57-4Delta-Sleep Inducing PeptideSODSuperoxide DismutaseInhibitorinhibitorinhibit

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δ-Sleep Inducing Peptide (Synonyms: Delta-Sleep Inducing Peptide)

Revisión del cliente

Other Forms of δ-Sleep Inducing Peptide:

δ-Sleep Inducing Peptide Related Antibodies

Recomendaciones destacadas

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Actividad biológica

Protocolo

Pureza y Documentación

Referencias

Revisión del cliente

δ-Sleep Inducing Peptide Related Classifications

Calculadora de molaridad

Calculadora de dilución

The molarity calculator equation

The dilution calculator equation

Keywords:

Productos vistos recientemente:

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