1. Metabolic Enzyme/Protease Others
  2. Drug Metabolite Drug Intermediate
  3. Acetaminosalol

Acetaminosalol, a merged ester NSAID–APAP hybrid, is a metabolite of Benorylate (HY-107795) and a prodrug of Acetaminophen (HY-66005) and Aalicylic acid (HY-B0167). Acetaminosalol can be used for the research of acute rheumatism.

For research use only. We do not sell to patients.

Acetaminosalol

Acetaminosalol Chemical Structure

CAS No. : 118-57-0

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Description

Acetaminosalol, a merged ester NSAID–APAP hybrid, is a metabolite of Benorylate (HY-107795) and a prodrug of Acetaminophen (HY-66005) and Aalicylic acid (HY-B0167). Acetaminosalol can be used for the research of acute rheumatism[1].

Cellular Effect
Cell Line Type Value Description References
CHO Inhibition
102.732 %
Compound: ACETAMINOSALOL
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
[PMID: 23571415]
CHO Inhibition
103.085 %
Compound: ACETAMINOSALOL
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM
[PMID: 23571415]
In Vitro

Acetaminosalol (Compound 47) is a chemically stable prodrug that resists gastric juice hydrolysis, undergoes enzymatic hydrolysis in human plasma and rat liver homogenate to release active Aalicylic acid (HY-B0167) and Acetaminophen (HY-66005)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

271.27

Formula

C15H13NO4

CAS No.
SMILES

O=C(OC1=CC=C(C=C1)NC(=O)C)C=2C=CC=CC2O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Acetaminosalol
Cat. No.:
HY-W725454
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