Acetylcholinesterase, Fly head  (Synonyms: ACHE; EC 3.1.1.7)

Acetylcholinesterase, Fly head (ACHE; EC 3.1.1.7) is a cholinergic enzyme mainly found in neuromuscular junctions and cholinergic type chemical synapses used in biochemical research. Acetylcholinesterase, Fly head catalyzes the breakdown or hydrolysis of acetylcholine and some other choline esters that act as neurotransmitters into acetate and choline. Acetylcholinesterase, Fly head's main role is to terminate neuronal transmission and signaling between synapses to prevent ACh spread and activation of nearby receptors^[1].

Product Information
Molecular weight: 280 kDa (gel filtrationl, tetramer)
Isoelectric point: 5.5

Instructions
Soluble in water (dissolved below 10 mg/mL), fresh preparation is recommended. Or dissolved in buffer according to specific experimental references (e.g. 1 mg/mL dissolved in 20 mM Tris HCl buffer pH 7.5).

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

9000-81-1

Solid

White to light brown

[Acetylcholinesterase, Fly head]

3.1.1.7

≥200 U/g soild

One unit is defined as the amount of enzyme that decompose 1 μmol of iodized thioacetylcholine (ATCI) per minute at 37°C , in 0.1 mol/L pH = 8.0 phosphoric acid buffer

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Israel Silman, et al. Acetylcholinesterase: how is structure related to function? Chem Biol Interact. 2008 Sep 25;175(1-3):3-10.  [Content Brief]