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(−)-Acutumine is a tetracyclic chloroalkaloid that exhibits selective cytotoxicity to cultured human T cells and memory-enhancing properties in the Wistar rat model.

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(−)-Acutumine

(−)-Acutumine Chemische Struktur

CAS. Nr. : 17088-50-5

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Beschreibung

(−)-Acutumine is a tetracyclic chloroalkaloid that exhibits selective cytotoxicity to cultured human T cells and memory-enhancing properties in the Wistar rat model[1].

Cellular Effect
Cell Line Type Value Description References
HepG2 2.2.15 CC50
>2.989 mM
Compound: 3
Cytotoxicity against human Hep G2.2.15 cells
Cytotoxicity against human Hep G2.2.15 cells
[PMID: 17723297]
HepG2 2.2.15 IC50
>2.98 mM
Compound: 3
Antiviral activity against HBV transfected Hep G2.2.15 cells assessed as inhibition of e antigen HBsAg secretion
Antiviral activity against HBV transfected Hep G2.2.15 cells assessed as inhibition of e antigen HBsAg secretion
[PMID: 17723297]
HepG2 2.2.15 IC50
>2.989 mM
Compound: 3
Antiviral activity against HBV transfected Hep G2.2.15 cells assessed as inhibition of surface antigen HBsAg secretion
Antiviral activity against HBV transfected Hep G2.2.15 cells assessed as inhibition of surface antigen HBsAg secretion
[PMID: 17723297]
Molekulargewicht

397.85

Formel

C19H24ClNO6

CAS. Nr.
SMILES

COC([C@@]12[C@](C3)(CCN2C)[C@@]4([C@H](C1)Cl)[C@@H](C(OC)=CC4=O)O)=C(OC)C3=O

Structure Classification
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(−)-Acutumine
Art. -Nr.:
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