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AIE-ER is a specific endoplasmic reticulum (ER) fluorescent probe (green channel: λex=405 nm, λem=450~650 nm) that exhibits remarkable photostability, high brightness, and low working concentration. AIE-ER may provide an avenue for studying diseases related to the endoplasmic reticulum.

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AIE-ER

AIE-ER 構造式

CAS 番号 : 2653341-17-2

容量 価格(税別) 在庫状況 数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
USD 271 在庫あり
Solution
10 mM * 1 mL in DMSO USD 271 在庫あり
Solid
5 mg $189 在庫あり
10 mg $315 在庫あり
25 mg $660 在庫あり
50 mg $1056 在庫あり
100 mg $1690 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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  • 純度とドキュメンテーション

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製品説明

AIE-ER is a specific endoplasmic reticulum (ER) fluorescent probe (green channel: λex=405 nm, λem=450~650 nm) that exhibits remarkable photostability, high brightness, and low working concentration. AIE-ER may provide an avenue for studying diseases related to the endoplasmic reticulum[1].

体外実験

AIE-ER (1-10 μM; 24 h) exhibits low cytotoxicity in HeLa cells, maintaining good cell viability (> 75%) even at a concentration of 10 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

652.80

分子式

C40H36N4O3S

CAS 番号
Appearance

Solid

Color

Light yellow to green yellow

SMILES

N#C/C(C1=CC=C(C2=CC=C(S(NC(NC3CCCCC3)=O)(=O)=O)C=C2)C=C1)=C\C4=CC=C(N(C5=CC=CC=C5)C6=CC=CC=C6)C=C4

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶剤 & 溶解度
体外: 

DMSO : ≥ 100 mg/mL (153.19 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5319 mL 7.6593 mL 15.3186 mL
5 mM 0.3064 mL 1.5319 mL 3.0637 mL
10 mM 0.1532 mL 0.7659 mL 1.5319 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始)

C1

×
体積 (開始)

V1

=
濃度 (終了)

C2

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体積 (終了)

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5319 mL 7.6593 mL 15.3186 mL 38.2966 mL
5 mM 0.3064 mL 1.5319 mL 3.0637 mL 7.6593 mL
10 mM 0.1532 mL 0.7659 mL 1.5319 mL 3.8297 mL
15 mM 0.1021 mL 0.5106 mL 1.0212 mL 2.5531 mL
20 mM 0.0766 mL 0.3830 mL 0.7659 mL 1.9148 mL
25 mM 0.0613 mL 0.3064 mL 0.6127 mL 1.5319 mL
30 mM 0.0511 mL 0.2553 mL 0.5106 mL 1.2766 mL
40 mM 0.0383 mL 0.1915 mL 0.3830 mL 0.9574 mL
50 mM 0.0306 mL 0.1532 mL 0.3064 mL 0.7659 mL
60 mM 0.0255 mL 0.1277 mL 0.2553 mL 0.6383 mL
80 mM 0.0191 mL 0.0957 mL 0.1915 mL 0.4787 mL
100 mM 0.0153 mL 0.0766 mL 0.1532 mL 0.3830 mL
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

製品名:
AIE-ER
製品番号:
HY-D2299
数量:
MCE 日本正規代理店: