Aminoacyl tRNA synthetase-IN-4

Cat. No.: HY-128189: Ficha de datos Instrucciones de manejo
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Aminoacyl tRNA synthetase-IN-4 (Compound 1l) is an inhibitor of Aminoacyl tRNA synthetase, with an IC₅₀ of 0.026 μM for C.albicans prolyl-tRNA synthetase. Aminoacyl tRNA synthetase-IN-4 can be used for antifungal research.

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Aminoacyl tRNA synthetase-IN-4 Estructura química

No. CAS : 342017-94-1

Tamaño	Stock	Cantidad
50 mg	Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 mg	Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 mg	Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
1 g	Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
5 g	Obtener un presupuesto
10 g	Obtener un presupuesto

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Descripciòn

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	CC₅₀	>20 μM Compound: MMV247764	Cytotoxicity against HEK293 cells (CO-ADD:MA_007); CC50 by cell viability assay in DMEM (10% FBS) media using TC plates, by Resazurin F(560/590) Cytotoxicity against HEK293 cells (CO-ADD:MA_007); CC50 by cell viability assay in DMEM (10% FBS) media using TC plates, by Resazurin F(560/590)	10.6019/CHEMBL4296181
MDCK	EC₅₀	2.2 μM Compound: C7	Antiviral activity against VSV infected in MDCK cells assessed as inhibition of VSV replication after 48 hrs by plaque assay Antiviral activity against VSV infected in MDCK cells assessed as inhibition of VSV replication after 48 hrs by plaque assay	[PMID: 23930152]

Peso molecular

362.61

Fòrmula

C₁₆H₉BrClNO₂

No. CAS

342017-94-1

SMILES

O=C(C1=CC(C2=CC=C(Br)C=C2)=NC3=CC=C(Cl)C=C13)O

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Yu XY, et al. A series of quinoline analogues as potent inhibitors of C. albicans prolyl tRNA synthetase. Bioorg Med Chem Lett. 2001 Feb 26;11(4):541-4. [Content Brief]