1. Metabolic Enzyme/Protease Anti-infection
  2. Aminoacyl-tRNA Synthetase Fungal
  3. Aminoacyl tRNA synthetase-IN-4

Aminoacyl tRNA synthetase-IN-4 (Compound 1l) is an inhibitor of Aminoacyl tRNA synthetase, with an IC50 of 0.026 μM for C.albicans prolyl-tRNA synthetase. Aminoacyl tRNA synthetase-IN-4 can be used for antifungal research.

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Aminoacyl tRNA synthetase-IN-4

Aminoacyl tRNA synthetase-IN-4 Chemische Struktur

CAS. Nr. : 342017-94-1

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Beschreibung

Aminoacyl tRNA synthetase-IN-4 (Compound 1l) is an inhibitor of Aminoacyl tRNA synthetase, with an IC50 of 0.026 μM for C.albicans prolyl-tRNA synthetase. Aminoacyl tRNA synthetase-IN-4 can be used for antifungal research[1].

Cellular Effect
Cell Line Type Value Description References
HEK293 CC50
>20 μM
Compound: MMV247764
Cytotoxicity against HEK293 cells (CO-ADD:MA_007); CC50 by cell viability assay in DMEM (10% FBS) media using TC plates, by Resazurin F(560/590)
Cytotoxicity against HEK293 cells (CO-ADD:MA_007); CC50 by cell viability assay in DMEM (10% FBS) media using TC plates, by Resazurin F(560/590)
10.6019/CHEMBL4296181
MDCK EC50
2.2 μM
Compound: C7
Antiviral activity against VSV infected in MDCK cells assessed as inhibition of VSV replication after 48 hrs by plaque assay
Antiviral activity against VSV infected in MDCK cells assessed as inhibition of VSV replication after 48 hrs by plaque assay
[PMID: 23930152]
Molekulargewicht

362.61

Formel

C16H9BrClNO2

CAS. Nr.
SMILES

O=C(C1=CC(C2=CC=C(Br)C=C2)=NC3=CC=C(Cl)C=C13)O

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

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