Talin 1 Antibody (YA6816)

製品番号: HY-P87123: データシート SDS COA User Guide for Antibodies
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Talin 1 Antibody (YA6816) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Talin 1.

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容量	価格（税別）	在庫状況	数量
10 μL	$96	在庫あり	Estimated Time of Arrival: December 31
50 μL	$252	在庫あり	Estimated Time of Arrival: December 31
100 μL	$408	在庫あり	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Verification Image
Background
説明
参考文献

製品説明

Talin 1 Antibody (YA6816) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Talin 1.

Host

Rabbit

Clonality

Recombinant,Monoclonal

分子量

Predicted band size: 270 kDa;

Observed band size: 270 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9Y490

Gene ID

7094 [NCBI]

Immunogen

Recombinant protein within human Talin 1 aa 1,700-2,000 / 2,541.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:2000

純度	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Verification Image

Western blot analysis of extracts from Hela (lane 1(20μg)) 、HepG2 (lane 2(20μg)) 、NIH-3T3 (lane 3(20μg)) and C6 (lane 4(20μg)) using Talin 1 Antibody (HY-P87123) . Proteins were transferred to a PVDF membrane and blocked with 5% nonfat dry milk5% nonfat dry milk in TBST for 1.5 hour at room temperature. The primary antibody (1/2000) and Loading control antibody (β Tubulin, 1/5000) was used in 5% nonfat dry milk in TBST at 4℃ overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/10,000) was used for 1 hour at room temperature.

Background

Function：High molecular weight cytoskeletal protein concentrated at regions of cell-matrix and cell-cell contacts. Involved in connections of major cytoskeletal structures to the plasma membrane. With KANK1 co-organize the assembly of cortical microtubule stabilizing complexes (CMSCs) positioned to control microtubule-actin crosstalk at focal adhesions (FAs) rims

Subcellular Localization：Cell projection, ruffle membrane,Cytoplasm, cytoskeleton,Cell surface,Cell junction, focal adhesion

Expression：
Tissue_Specificity: Expressed at low to non-detectable levels in many tissues but highly expressed in skin and pancreas with other tissues including kidney cortex, endocervix, testis, pituitary, liver, and spleen also showing robust expression
Induction: By a combination of TGFB and EGF

Isoforms & Post-Translational Modification：Q9Y490 has two isomers: Q9Y490-1: 269767 Da (predicted); Q9Y490-2: 271420 Da (predicted).

Subunit：Part of a complex composed of THSD1, PTK2/FAK1, TLN1 and VCL (PubMed:29069646)

RRID

AB_3719266

Synonyms

ILWEQ antibody; Talin 1 antibody; Talin antibody; Talin-1 antibody; TLN 1 antibody; TLN antibody; Tln1 antibody; TLN1_HUMAN antibody;

ドキュメンテーション

Select Batch:

データシート (231 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/te-8-cell.html