Blue dextran (MW 2000000)  (Synonyms: Dextran blue (MW 2000000))

Blue dextran (Dextran blue) (MW 2000000) is a high-molecular-weight long-chain polymer of D-glucose. Blue dextran (MW 2000000) serves as an important model macromolecular drug and molecular weight estimation marker, and can be used as a standard for gel permeation chromatography. The release of Blue dextran (MW 2000000) from alginate microspheres is regulated by preparation conditions; its release rate in a pH 6.8 environment is significantly faster than that in pH 1.2, and it exhibits release characteristics close to zero-order kinetics under this condition^[1][2][3].

The release rate of Blue dextran (MW 2000000) (Blue dextran/sodium alginate ratio=1:1-1:6; 8 h) from sodium alginate microspheres slows down as the Blue dextran/sodium alginate ratio decreases, with the slowest release observed at a ratio of 1:6 and the fastest release at a ratio of 1:1^[1].
The release of Blue dextran (MW 2000000) (crosslinking for 6-60 min; release monitoring for 8 h) from alginate microspheres is minimally affected by crosslinking time; compared with microspheres crosslinked for 6 min, those crosslinked for 60 min show a slightly slower release rate, while no significant difference is observed when crosslinking time exceeds 6 min^[1].
The molecular mass of Blue dextran (MW 2000000) matches that of the dextran produced by free cells of *Leuconostoc mesenteroides* KIBGE HA1^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2000000.00

87915-38-6

Solid

Dark blue to black

[Blue dextran (MW 2000000)]

Room temperature in continental US; may vary elsewhere.

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. Kim C K, et al. The controlled release of blue dextran from alginate beads[J]. International Journal of pharmaceutics, 1992, 79(1-3): 11-19.

  [2]. Qader S A U, et al. Low molecular weight dextran: Immobilization of cells of Leuconostoc mesenteroides KIBGE HA1 on calcium alginate beads[J]. Carbohydrate Polymers, 2012, 87(4): 2589-2592.

  [3]. Qader SA, et al. Continuous Production of Dextran from Immobilized Cells of Leuconostoc mesenteroides KIBGE HA1 Using Acrylamide as a Support. Indian J Microbiol. 2011;51(3):279-282.