Blue dextran (MW 10000)
Blue dextran (Dextran blue) (MW 10000) is a 10 kDa osmotic dextran. Blue dextran (MW 10000) penetrates all sublayers of the pre-epithelial mucus gel layer in the rat distal colon and is taken up by the nuclei of surface cells in the rat distal colonic mucosa. Blue dextran (MW 10000) is not blocked by the pre-epithelial mucus gel layer of the rat distal colon, which acts as a diffusion barrier.
For research use only. We do not sell to patients.
- CAS No.: 87915-38-6
- Molecular Weight:10000 (Average)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Blue dextran (MW 10000) (Dextran blue (MW 10000)) is a conjugate formed by the binding of dextran to the Cibacron Blue 3G-A ligand, and is mainly used for the purification of human serum albumin[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Wistar AS/Ztm; Lewis (adult, both sexes, mean body weight 302 ± 52 g)[2]
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Dosage:10 mg/mL (200 μl total volume)
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Administration:intraluminally into distal colon segments
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Result:Traversed the 30-50 μm thick pre-epithelial mucus gel layer and was present in the nuclei of superficial distal colonic mucosal cells at 1 minute after administration.
Was homogeneously distributed throughout all pre-epithelial mucus gel layer sublayers and present in most superficial mucosal cells at 2 minutes after administration.
Remained distributed across all pre-epithelial mucus gel layer sublayers and was present in superficial mucosal cells at 10 minutes after administration.
Chemical Information
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CAS No. 87915-38-6
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Molecular Weight 10000 (Average)
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SMILES
[Blue dextran (MW 10000)]
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Synonyms
Dextran blue (MW 10000)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Blue dextran (MW 10000) Related Classifications
HY-W134328B Related Classifications
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