2. Neuronal Signaling Protein Tyrosine Kinase/RTK Apoptosis
  3. Trk Receptor Apoptosis
  4. BNN27

BNN27 is the agonist for TrkA receptor and p75NTR receptor, that exhibits neurotrophic and anti-apoptotic effects. BNN27 increases the levels of glutamate, GABA, and glutamine in the rat hippocampus and prefrontal cortex, improves glutamate turnover. BNN27 exhibits neuroprotective efficacy in mouse amyotrophic lateral sclerosis (ALS) model, exhibits anti-inflammatory efficacy in experimental autoimmune encephalomyelitis (EAE) model, exhibits retinal protective efficacy in rat diabete models. BNN27 is blood-brain barrier penetrable.

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BNN27

BNN27 화학구조

CAS No. : 1195795-81-3

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BNN27 Related Antibodies

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제품 설명

BNN27 is the agonist for TrkA receptor and p75NTR receptor, that exhibits neurotrophic and anti-apoptotic effects. BNN27 increases the levels of glutamate, GABA, and glutamine in the rat hippocampus and prefrontal cortex, improves glutamate turnover. BNN27 exhibits neuroprotective efficacy in mouse amyotrophic lateral sclerosis (ALS) model, exhibits anti-inflammatory efficacy in experimental autoimmune encephalomyelitis (EAE) model, exhibits retinal protective efficacy in rat diabete models. BNN27 is blood-brain barrier penetrable[1].

분자량

332.48

화학식

C21H32O3
CAS No.
SMILES

C[C@@]12[C@]3(CC[C@@]1([H])[C@@]4([H])[C@]([C@@]5(C(C[C@H](CC5)O)=CC4)C)([H])CC2)[C@H](O3)CO
선적

Room temperature in continental US; may vary elsewhere.
보관

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순도&문서
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Keywords:

BNN271195795-81-3BNN 27BNN-27Trk ReceptorApoptosisTropomyosin related kinase receptor Alzheimer's diseaseADamyotrophic lateral sclerosisALSautoimmune encephalomyelitisEAEBBBInhibitorinhibitorinhibit

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BNN27
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HY-170409
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