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  4. Chlorphenesin carbamate

Chlorphenesin carbamate  (Synonyms: Maolate; U 19646)

製品番号: HY-107944 純度: 99.12%
COA 取扱説明書 Technical Support

Chlorphenesin carbamate is a centrally acting skeletal muscle relaxant, as well as a derivate of Chlorphenesin (HY-A0133). Chlorphenesin carbamate can be used for the research of pain and discomfort related to skeletal muscle trauma and inflammation. Chlorphenesin carbamate is a selective blocker of polysynaptic pathways at the spinal and supra-spinal levels. Antinociceptive effect.

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Chlorphenesin carbamate

Chlorphenesin carbamate 構造式

CAS 番号 : 886-74-8

容量 価格（税別） 在庫状況 数量
>無料サンプル (0.1 - 0.2 mg)   今すぐ申し込む  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 55 在庫あり
Solution
10 mM * 1 mL in DMSO USD 55 在庫あり
Solid
10 mg $50 在庫あり
25 mg $95 在庫あり
50 mg $150 在庫あり
100 mg $220 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

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Other Forms of Chlorphenesin carbamate:

Chlorphenesin carbamate 関連抗体

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製品説明

Chlorphenesin carbamate is a centrally acting skeletal muscle relaxant, as well as a derivate of Chlorphenesin (HY-A0133). Chlorphenesin carbamate can be used for the research of pain and discomfort related to skeletal muscle trauma and inflammation[1]. Chlorphenesin carbamate is a selective blocker of polysynaptic pathways at the spinal and supra-spinal levels[2]. Antinociceptive effect[3].

体内実験

Chlorphenesin carbamate (CPC; 50 mg/kg i.v.) inhibits the mono (MSR) and poly-synaptic reflex (PSR), the latter being more susceptible than the former to CPC depression. Chlorphenesin carbamate has an apparent depressant action on the spinal neuron, and it hyperpolarized both the ventral and dorsal roots of the isolated frog spinal cord[2].
Chlorphenesin carbamate (CPC) has an antinociceptive action in adjuvant arthritic rats. Chlorphenesin carbamate (100-400 mg/kg, p.o.) has a dose-dependent antinociceptive effect in the behavioral study. Chlorphenesin carbamate (25-50 mg/kg, i.v.) depresses the evoked neuronal responses of nociceptive neurons in the ventrobasal thalamus (VB) in the electrophysiological study. Chlorphenesin carbamate (50 mg/kg, i.v.) depresses the spontaneous firings of the VB nociceptive neurons[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Wister rats weighing 200-300 g[3]
Dosage: 50 mg/kg
Administration: Intravenously administered
Result: Significantly inhibited PSR, with the maximum inhibition at 40 min after the drug administration.
臨床実験
分子量

245.66

分子式

C10H12ClNO4
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

OC(COC1=CC=C(Cl)C=C1)COC(N)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
体外: 

DMSO : 125 mg/mL (508.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0707 mL 20.3533 mL 40.7067 mL
5 mM 0.8141 mL 4.0707 mL 8.1413 mL
10 mM 0.4071 mL 2.0353 mL 4.0707 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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一般には略語で表示されます：C1V1 = C2V2

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純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.0707 mL 20.3533 mL 40.7067 mL 101.7667 mL
5 mM 0.8141 mL 4.0707 mL 8.1413 mL 20.3533 mL
10 mM 0.4071 mL 2.0353 mL 4.0707 mL 10.1767 mL
15 mM 0.2714 mL 1.3569 mL 2.7138 mL 6.7844 mL
20 mM 0.2035 mL 1.0177 mL 2.0353 mL 5.0883 mL
25 mM 0.1628 mL 0.8141 mL 1.6283 mL 4.0707 mL
30 mM 0.1357 mL 0.6784 mL 1.3569 mL 3.3922 mL
40 mM 0.1018 mL 0.5088 mL 1.0177 mL 2.5442 mL
50 mM 0.0814 mL 0.4071 mL 0.8141 mL 2.0353 mL
60 mM 0.0678 mL 0.3392 mL 0.6784 mL 1.6961 mL
80 mM 0.0509 mL 0.2544 mL 0.5088 mL 1.2721 mL
100 mM 0.0407 mL 0.2035 mL 0.4071 mL 1.0177 mL
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Chlorphenesin carbamate Related Classifications

  • Molarity Calculator

  • Dilution Calculator

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Chlorphenesin carbamate886-74-8Maolate U 19646U19646U 19646U-19646Drug DerivativeDrug derivativeCentrallyskeletalmusclerelaxantpaintraumainflammationAntinociceptiveInhibitorinhibitorinhibit

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製品名:
Chlorphenesin carbamate
製品番号:
HY-107944
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