Cyclohexane-1,3-dione

Cat. No.: HY-W007466 Purity: 99.99%: Data Sheet
COA

SDS
Handling Instructions
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Technical Support

Cyclohexane-1,3-dione is a drug intermediate, and its derivatives can exhibit significant tyrosine kinase inhibitory activity and anti-tumor activity.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Cyclohexane-1,3-dione 화학구조

CAS No. : 504-02-9

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
100 g	해외재고보유	Estimated Time of Arrival: December 31
> 100 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

Other Forms of Cyclohexane-1,3-dione:

Cyclohexane-1,3-dione-¹³C₃ 견적 받기
Cyclohexane-1,3-dione-¹³C₆ 견적 받기

1 Publications Citing Use of MCE Cyclohexane-1,3-dione

•Autophagy. 2026 Apr;22(4):763-778. [Abstract]

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•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity
순도&문서
References
고객리뷰

제품 설명

Cyclohexane-1,3-dione is a drug intermediate, and its derivatives can exhibit significant tyrosine kinase inhibitory activity and anti-tumor activity^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
LS180	IC₅₀	> 100 3 Compound: 128	Anticancer activity against human LS180 assessed as inhibition in cell viability Anticancer activity against human LS180 assessed as inhibition in cell viability	[PMID: 33276991]
LS180	IC₅₀	>100 3 Compound: 128	Anticancer activity against human LS180 assessed as inhibition in cell viability Anticancer activity against human LS180 assessed as inhibition in cell viability	[PMID: 33276991]
MCF7	IC₅₀	100 3 Compound: 128	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 96 hrs by SRB assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 96 hrs by SRB assay	[PMID: 33276991]
MCF7	IC₅₀	100 3 Compound: 128	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 96 hrs by SRB assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 96 hrs by SRB assay	[PMID: 33276991]
MCF7	IC₅₀	100 3 Compound: 128	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 96 hrs by SRB assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 96 hrs by SRB assay	[PMID: 33276991]

분자량

112.13

화학식

C₆H₈O₂

CAS No.

504-02-9

Appearance

Solid

Color

White to light yellow

SMILES

O=C1CC(CCC1)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

용액&용해도

In Vitro:

DMSO : ≥ 100 mg/mL (891.82 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	8.9182 mL	44.5911 mL	89.1822 mL
5 mM	1.7836 mL	8.9182 mL	17.8364 mL
10 mM	0.8918 mL	4.4591 mL	8.9182 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.99%

Select Batch:

Data Sheet (273 KB) SDS (614 KB)

COA (248 KB) RP-HPLC (452 KB) LCMS (97 KB)

Handling Instructions (2659 KB)

References

[1]. Daoui O, et al. Cyclohexane-1,3-dione Derivatives as Future Therapeutic Agents for NSCLC: QSAR Modeling, In Silico ADME-Tox Properties, and Structure-Based Drug Designing Approach. ACS Omega. 2023 Jan 19;8(4):4294-4319. [Content Brief]

[2]. Megally Abdo NY, et al. Uses of cyclohexane-1,3-dione for the synthesis of 1,2,4-triazine derivatives as anti-proliferative agents and tyrosine kinases inhibitors. Bioorg Chem. 2020 Apr;97:103667. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	8.9182 mL	44.5911 mL	89.1822 mL	222.9555 mL
	5 mM	1.7836 mL	8.9182 mL	17.8364 mL	44.5911 mL
	10 mM	0.8918 mL	4.4591 mL	8.9182 mL	22.2956 mL
	15 mM	0.5945 mL	2.9727 mL	5.9455 mL	14.8637 mL
	20 mM	0.4459 mL	2.2296 mL	4.4591 mL	11.1478 mL
	25 mM	0.3567 mL	1.7836 mL	3.5673 mL	8.9182 mL
	30 mM	0.2973 mL	1.4864 mL	2.9727 mL	7.4319 mL
	40 mM	0.2230 mL	1.1148 mL	2.2296 mL	5.5739 mL
	50 mM	0.1784 mL	0.8918 mL	1.7836 mL	4.4591 mL
	60 mM	0.1486 mL	0.7432 mL	1.4864 mL	3.7159 mL
	80 mM	0.1115 mL	0.5574 mL	1.1148 mL	2.7869 mL
	100 mM	0.0892 mL	0.4459 mL	0.8918 mL	2.2296 mL