2. Anti-infection
  3. HCV
  4. Danoprevir sodium

Danoprevir sodium  (Synonyms: ITMN-191 sodium; R7227 sodium; RO5190591 sodium)

Cat. No.: HY-10239
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Danoprevir (sodium) (ITMN-191) is a compound used to inhibit hepatitis C virus infection.

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No. CAS : 916826-48-7

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Top Publications Citing Use of Products

    Danoprevir sodium purchased from MedChemExpress. Usage Cited in: Virology. 2014 May;456-457:300-9.  [Abstract]

    Jurkat cells are transfected with plasmids expressing (A) HCV NS3/4A or (B) HPgV NS3/4AB-HA. Telaprevir, Boceprevir, and Danoprevir are added at concentrations of 100 µM, 16.6 µM, 2.7 µM, or 0 µM in 0.1% DMSO. Lysates are harvested after 24 h and resolved by immunoblots probed with anti-HCV NS3 (A) or anti-HA (B). The position of HCV NS3/4A (~75kDa), HCV NS3 (~73kDa), NS3/4AB-HA, and NS4B-HA (~30kDa) are indicated. Molecular markers are on the right.

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    Descripciòn

    Danoprevir (sodium) (ITMN-191) is a compound used to inhibit hepatitis C virus infection.

    Ensayo clínico
    Peso molecular

    754.82

    Fòrmula

    C35H46FN5NaO9S
    No. CAS
    SMILES

    O=S(NC([C@]1(C[C@@]1([H])/C=C/CCCCC[C@@H]2NC(OC(C)(C)C)=O)NC([C@@](C3)([H])N(C[C@@H]3OC(N4CC(C(F)=CC=C5)=C5C4)=O)C2=O)=O)=O)(C6CC6)=O.[Na]
    Envío

    Room temperature in continental US; may vary elsewhere.
    Almacenamiento

    Please store the product under the recommended conditions in the Certificate of Analysis.
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    Danoprevir sodium Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Danoprevir916826-48-7ITMN-191R7227RO5190591ITMN191ITMN 191R 7227R-7227RO 5190591RO-5190591HCVHepatitis C virusInhibitorinhibitorinhibit

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    Nombre del producto:
    Danoprevir sodium
    Cat. No.:
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