2. Anti-infection
  3. HCV
  4. Deleobuvir

Deleobuvir (BI 207127), a chemical probe, is a potent non-nucleoside hepatitis C virus (HCV) NS5B polymerase inhibitor.

Para uso exclusivo en investigación. No vendemos a pacientes.

The Deleobuvir was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.

Deleobuvir

Deleobuvir Estructura química

No. CAS : 863884-77-9

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1 mg En stock
5 mg   Obtener un presupuesto  
10 mg   Obtener un presupuesto  

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Other Forms of Deleobuvir:

Deleobuvir Related Antibodies

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Descripciòn

Deleobuvir (BI 207127), a chemical probe, is a potent non-nucleoside hepatitis C virus (HCV) NS5B polymerase inhibitor.

Ensayo clínico
Peso molecular

653.57

Fòrmula

C34H33BrN6O3
No. CAS
Appearance

Solid

Color

White to light yellow

SMILES

CN1C(C2=NC=C(Br)C=N2)=C(C3CCCC3)C4=CC=C(C(NC5(C(N(C6=C7)C)=NC6=CC=C7/C=C/C(O)=O)CCC5)=O)C=C41
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvente y solubilidad
In Vitro: 

DMSO : 6.6 mg/mL (10.10 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5301 mL 7.6503 mL 15.3006 mL
5 mM 0.3060 mL 1.5301 mL 3.0601 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 99.13%

SDS (252 KB)

COA (249 KB) HNMR (262 KB) RP-HPLC (170 KB) MS (135 KB)

Instrucciones de manejo (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5301 mL 7.6503 mL 15.3006 mL 38.2514 mL
5 mM 0.3060 mL 1.5301 mL 3.0601 mL 7.6503 mL
10 mM 0.1530 mL 0.7650 mL 1.5301 mL 3.8251 mL
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Deleobuvir Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Deleobuvir863884-77-9BI 207127BI207127BI-207127HCVHepatitis C virusInhibitorinhibitorinhibit

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Nombre del producto:
Deleobuvir
Cat. No.:
HY-12634
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SAFETY DATA SHEET (SDS)

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