Deoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one

Cat. No.: HY-154171 Purity: 99.87%: Data Sheet
COA

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Handling Instructions
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Deoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one (Compound dP) exhibits mutagenicity for Escherichia coli and Salmonella typhimurium, that induces the conversion between GC and AT through replication error. eoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one is stable in Escherichia coli, and can be detected at wavelength >300 nM.

For research use only. We do not sell to patients.

Deoxyribosyl dihydropyrimido[4,5-c][1,2]oxazin-7-one Chemical Structure

CAS No. : 126128-42-5

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

269.25

Formula

C₁₁H₁₅N₃O₅

CAS No.

126128-42-5

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1C[C@H](N2C=C3C(NC2=O)=NOCC3)O[C@@H]1CO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (464.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7140 mL	18.5701 mL	37.1402 mL
5 mM	0.7428 mL	3.7140 mL	7.4280 mL
10 mM	0.3714 mL	1.8570 mL	3.7140 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.87%

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Data Sheet (273 KB) SDS (252 KB)

COA (253 KB) HNMR (278 KB) RP-HPLC (275 KB) MS (71 KB)

Handling Instructions (2659 KB)

References

[1]. Negishi K, et al., The mechanism of mutation induction by a hydrogen bond ambivalent, bicyclic N4-oxy-2'-deoxycytidine in Escherichia coli. Nucleic Acids Res. 1997 Apr 15;25(8):1548-52. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.7140 mL	18.5701 mL	37.1402 mL	92.8505 mL
	5 mM	0.7428 mL	3.7140 mL	7.4280 mL	18.5701 mL
	10 mM	0.3714 mL	1.8570 mL	3.7140 mL	9.2851 mL
	15 mM	0.2476 mL	1.2380 mL	2.4760 mL	6.1900 mL
	20 mM	0.1857 mL	0.9285 mL	1.8570 mL	4.6425 mL
	25 mM	0.1486 mL	0.7428 mL	1.4856 mL	3.7140 mL
	30 mM	0.1238 mL	0.6190 mL	1.2380 mL	3.0950 mL
	40 mM	0.0929 mL	0.4643 mL	0.9285 mL	2.3213 mL
	50 mM	0.0743 mL	0.3714 mL	0.7428 mL	1.8570 mL
	60 mM	0.0619 mL	0.3095 mL	0.6190 mL	1.5475 mL
	80 mM	0.0464 mL	0.2321 mL	0.4643 mL	1.1606 mL
	100 mM	0.0371 mL	0.1857 mL	0.3714 mL	0.9285 mL