1. Apoptosis
    PROTAC
  2. Bcl-2 Family
    Ligand for Target Protein for PROTAC
  3. Desmorpholinyl Navitoclax-NH-Me

Desmorpholinyl Navitoclax-NH-Me (Synonyms: Desmorpholinyl ABT-263-NH-Me)

Cat. No.: HY-131232
Handling Instructions

Desmorpholinyl Navitoclax-NH-Me is a Bcl-xL inhibitor. Desmorpholinyl Navitoclax-NH-Me and a CRBN ligand for the E3 ubiquitin ligase can be used in the synthesis of PROTAC BCL-XL degrader XZ739 (HY-133557).

For research use only. We do not sell to patients.

Desmorpholinyl Navitoclax-NH-Me Chemical Structure

Desmorpholinyl Navitoclax-NH-Me Chemical Structure

CAS No. : 2365172-82-1

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Description

Desmorpholinyl Navitoclax-NH-Me is a Bcl-xL inhibitor. Desmorpholinyl Navitoclax-NH-Me and a CRBN ligand for the E3 ubiquitin ligase can be used in the synthesis of PROTAC BCL-XL degrader XZ739 (HY-133557)[1][2].

Molecular Weight

918.55

Formula

C₄₄H₅₁ClF₃N₅O₅S₃

CAS No.

2365172-82-1

SMILES

O=C(C1=CC=C(N2CCN(CC3=C(C4=CC=C(Cl)C=C4)CCC(C)(C)C3)CC2)C=C1)NS(C5=CC(S(=O)(C(F)(F)F)=O)=C(N[[email protected]@H](CSC6=CC=CC=C6)CCNC)C=C5)(=O)=O

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Desmorpholinyl Navitoclax-NH-MeDesmorpholinyl ABT-263-NH-MeBcl-2 FamilyLigand for Target Protein for PROTACTarget Protein-binding MoietyInhibitorinhibitorinhibit

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Desmorpholinyl Navitoclax-NH-Me
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HY-131232
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