EPO mimetic peptide-1  (Synonyms: EMP-1)

EPO mimetic peptide-1 (EMP-1), a 20 amino acid peptide. EPO mimetic peptide-1 stimulates cell proliferation, affects cell cycle and induces the production of reticulocytes in vivo^[1].

EPO mimetic peptide-1 shows inhibition of tracer ¹²⁵I-labeled EPO binding with an IC₅₀ value of 0.2 μM^[1].
EPO mimetic peptide-1 (0-50 mM; 48 h) stimulates proliferation of both TF-1 and B6Sut cells in a dose-dependent manner^[1].
EPO mimetic peptide-1 (1 and 10 μM) promots erythroid colony formation from human peripheral blood and murine bone marrow^[1].
EPO mimetic peptide-1 (10 μM; 10 min) induces the phosphorylation of proteins^[1].
EPO mimetic peptide-1 (1 and 10 μM; 0-18 h) affects cell cycle^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

EPO mimetic peptide-1 (1-2 mg; once) induces the production of reticulocytes over the background of endogenous in normal, untreated mice containing endogenous basal levels of EPO mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2092.36

C₉₄H₁₃₄N₂₆O₂₅S₂

180088-82-8

Gly-Gly-Thr-Tyr-Ser-Cys-His-Phe-Gly-Pro-Leu-Thr-Trp-Val-Cys-Lys-Pro-Gln-Gly-Gly-NH2 (disulfide bridge:Cys6-Cys15)

GGTYSCHFGPLTWVCKPQGG-NH2 (disulfide bridge:Cys6-Cys15)

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Wrighton NC, et al. Small peptides as potent mimetics of the protein hormone erythropoietin. Science. 1996 Jul 26;273(5274):458-64.  [Content Brief]