Ethylene glycol dimethacrylate

Name: Ethylene glycol dimethacrylate
Brand: MedChemExpress
SKU: HY-W014940
Rating: 4.5 (0 reviews)

Cat. No.: HY-W014940 Purity: 98.91%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Ethylene glycol dimethacrylate is a diester formed by the condensation of Ethylene glycol (HY-Y0338) and Methacrylic acid. Ethylene glycol dimethacrylate is a cross-linking agent for polymers. Ethylene glycol dimethacrylate increases Apoptosis, GPx4, SOD2, ROS. Ethylene glycol dimethacrylate is cytotoxic and genotoxic. Ethylene glycol dimethacrylate exhibits cross-linking activity, enhancing the mechanical properties and stability of materials.

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Ethylene glycol dimethacrylate 화학구조

CAS No. : 97-90-5

사이즈	재고	수량
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Liquid
50 g	해외재고보유	Estimated Time of Arrival: December 31
100 g	해외재고보유	Estimated Time of Arrival: December 31
250 g	해외재고보유	Estimated Time of Arrival: December 31
500 g	해외재고보유	Estimated Time of Arrival: December 31
> 100 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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•Related Small Molecules:

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View All Isoforms

GPX1 GPX4

Biological Activity
순도&문서
References
고객리뷰

제품 설명

IC₅₀ & Target

GPX4

In Vitro

Ethylene glycol dimethacrylate (0.005-10 mM; 24 h) reduces viability and increases apoptosis in human gingival fibroblasts^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Real Time qPCR^[1]

Cell Line:	Human gingival fibroblasts
Concentration:	0.1 mM, 1 mM, 5 mM
Incubation Time:	6 h
Result:	Increased the mRNA expression of the detoxifying enzymes glutathione peroxidase 4 (GPx4) and superoxide dismutase 2, mitochondrial (SOD2).

분자량

198.22

화학식

C₁₀H₁₄O₄

CAS No.

97-90-5

Appearance

Liquid

Color

Colorless to light yellow

SMILES

C=C(C)C(OCCOC(C(C)=C)=O)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : ≥ 100 mg/mL (504.49 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.0449 mL	25.2245 mL	50.4490 mL
5 mM	1.0090 mL	5.0449 mL	10.0898 mL
10 mM	0.5045 mL	2.5224 mL	5.0449 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.52%

Select Batch:

Data Sheet (270 KB) SDS (394 KB)

COA (243 KB)

Handling Instructions (2659 KB)

References

[1]. Anna Bielecka-Kowalska, et al. Ethylene glycol dimethacrylate and diethylene glycol dimethacrylate exhibits cytotoxic and genotoxic effect on human gingival fibroblasts via induction of reactive oxygen species. Toxicol In Vitro. 2018 Mar:47:8-17. [Content Brief]

[2]. Wong B C F, et al. Effects of ethylene glycol dimethacrylate as cross-linker in ionic liquid gel polymer electrolyte based on poly (glycidyl methacrylate). International Journal of Polymer Analysis and Characterization, 2016, 21(2): 95-103.

[3]. Wang Y, et al. Physicochemical Characteristics and Slow Release Performances of Chlorpyrifos Encapsulated by Poly(butyl acrylate-co-styrene) with the Cross-Linker Ethylene Glycol Dimethacrylate. J Agric Food Chem. 2015 Jun 3;63(21):5196-204. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.0449 mL	25.2245 mL	50.4490 mL	126.1225 mL
	5 mM	1.0090 mL	5.0449 mL	10.0898 mL	25.2245 mL
	10 mM	0.5045 mL	2.5224 mL	5.0449 mL	12.6122 mL
	15 mM	0.3363 mL	1.6816 mL	3.3633 mL	8.4082 mL
	20 mM	0.2522 mL	1.2612 mL	2.5224 mL	6.3061 mL
	25 mM	0.2018 mL	1.0090 mL	2.0180 mL	5.0449 mL
	30 mM	0.1682 mL	0.8408 mL	1.6816 mL	4.2041 mL
	40 mM	0.1261 mL	0.6306 mL	1.2612 mL	3.1531 mL
	50 mM	0.1009 mL	0.5045 mL	1.0090 mL	2.5224 mL
	60 mM	0.0841 mL	0.4204 mL	0.8408 mL	2.1020 mL
	80 mM	0.0631 mL	0.3153 mL	0.6306 mL	1.5765 mL
	100 mM	0.0504 mL	0.2522 mL	0.5045 mL	1.2612 mL