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Fenarimol (EL 222) is a potent and orally active fungicide. Fenarimol also is a androgen receptor inhibitor with an IC50 value of 19 µM. Fenarimol decreases the mRNA expression of PBP C3, ODC, IGF-1.

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Fenarimol

Fenarimol Estructura química

No. CAS : 60168-88-9

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Descripciòn

Fenarimol (EL 222) is a potent and orally active fungicide. Fenarimol also is a androgen receptor inhibitor with an IC50 value of 19 µM. Fenarimol decreases the mRNA expression of PBP C3, ODC, IGF-1[1].

Cellular Effect
Cell Line Type Value Description References
L6 IC50
0.35 μM
Compound: 1
Antitrypanosomal activity against trypomastigotes of Trypanosoma cruzi Tulahuen expressing the beta- galactosidase gene infected rat L6 cells after 96 hrs
Antitrypanosomal activity against trypomastigotes of Trypanosoma cruzi Tulahuen expressing the beta- galactosidase gene infected rat L6 cells after 96 hrs
[PMID: 22536986]
L6 IC50
76.8 μM
Compound: 1
Cytotoxicity against rat L6 cells after 72 hrs by Alamar Blue assay
Cytotoxicity against rat L6 cells after 72 hrs by Alamar Blue assay
[PMID: 22536986]
Peso molecular

331.20

Fòrmula

C17H12Cl2N2O

No. CAS
Appearance

Solid

Color

Off-white to light yellow

SMILES

ClC1=CC=C(C(C2=CN=CN=C2)(C3=C(Cl)C=CC=C3)O)C=C1

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

Nombre del producto:
Fenarimol
Cat. No.:
HY-114913
Cantidad:
MCE Japan Authorized Agent: