2. Apoptosis
  3. Transferrin Receptor
  4. Ferrous bisglycinate

Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia.

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Ferrous bisglycinate

Ferrous bisglycinate Estructura química

No. CAS : 20150-34-9

Tamaño Precio Stock Cantidad
500 mg En stock
1 g En stock
5 g En stock
10 g En stock
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50 g En stock
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Ferrous bisglycinate Related Antibodies

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Descripciòn

Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia[1][2].

In Vitro

Ferrous bisglycinate (25-200 μM; 2 h) does not affect the Caco-2 cells viability[2].
Ferrous bisglycinate (25 μM; 2 h) increases ferritin content in the Caco-2 cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ferrous bisglycinate Related Antibodies

Cell Viability Assay[2]

Cell Line: Caco-2 cells
Concentration: 0, 25, 50, 100, 200 μM
Incubation Time: 2 hours
Result: Did not affect the viability of wild-type and divalent metal transporter 1 (DMT1) knockout Caco-2 cells.

Western Blot Analysis[2]

Cell Line: Caco-2 cells
Concentration: 25 μM
Incubation Time: 2 hours
Result: Increased ferritin content and decreased DMT1 expression levels significantly in the wild-type cells.
In Vivo

Ferrous bisglycinate (500 mg/kg iron; p.o.) exerts a protective effect on colitis in mice[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female C57BL/6 mice are induced colitis by dextran sodium sulfate (DSS)[3]
Dosage: 500 mg/kg iron
Administration: P.o. (add to the diet) for 10 days
Result: Had the best survival rates (100%).
Caused the least body lost (9% body loss).
Ensayo clínico
Peso molecular

203.96

Fòrmula

C4H8FeN2O4
No. CAS
Appearance

Solid

Color

Brown to breen

SMILES

O=C1[O-][Fe+2]2([O-]C(CN2)=O)NC1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvente y solubilidad
In Vitro: 

0.1 M HCl : 2 mg/mL (9.81 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9029 mL 24.5146 mL 49.0292 mL
5 mM 0.9806 mL 4.9029 mL 9.8058 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 2 mg/mL (9.81 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 98%

SDS (393 KB)

COA (251 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
0.1 M HCl 1 mM 4.9029 mL 24.5146 mL 49.0292 mL 122.5730 mL
5 mM 0.9806 mL 4.9029 mL 9.8058 mL 24.5146 mL
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Ferrous bisglycinate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ferrous bisglycinate20150-34-9Transferrin ReceptorTfRCD71ironfortificantssupplementsdeficiencyanemiaInhibitorinhibitorinhibit

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Nombre del producto:
Ferrous bisglycinate
Cat. No.:
HY-130078
Cantidad:
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