Fmoc-Val-Ala-aminomethyl acetate

製品番号: HY-156813 純度: 96.20%: Data Sheet SDS COA 取扱説明書
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Fmoc-Val-Ala-aminomethyl acetate (Compound 58b) is an ADC Linker, and can be used for synthesis of ADCs.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Fmoc-Val-Ala-aminomethyl acetate 構造式

CAS 番号 : 2505045-86-1

容量	価格（税別）	在庫状況	数量
>無料サンプル (0.1 - 0.2 mg)		今すぐ申し込む
>無料サンプル (0.1 - 0.2 mg)		今すぐ申し込む
25 mg	$280	在庫あり	Estimated Time of Arrival: December 31
50 mg	$450	在庫あり	Estimated Time of Arrival: December 31
100 mg	$720	在庫あり	Estimated Time of Arrival: December 31
250 mg	$944	在庫あり	Estimated Time of Arrival: December 31
1 g	$1226	在庫あり	Estimated Time of Arrival: December 31
5 g		お問い合わせ
10 g		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

ADC Linker アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

Fmoc-Val-Ala-aminomethyl acetate (Compound 58b) is an ADC Linker, and can be used for synthesis of ADCs^[1].

体外実験

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

481.54

分子式

C₂₆H₃₁N₃O₆

CAS 番号

2505045-86-1

Appearance

Solid

Color

White to off-white

SMILES

CC(OCNC([C@H](C)NC([C@H](C(C)C)NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=O)=O)=O

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

溶剤 & 溶解度

体外:

DMSO : 50 mg/mL (103.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0767 mL	10.3834 mL	20.7667 mL
5 mM	0.4153 mL	2.0767 mL	4.1533 mL
10 mM	0.2077 mL	1.0383 mL	2.0767 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 97.08%

Select Batch:

データシート (267 KB) SDS (393 KB)

COA (248 KB) HNMR (237 KB) LCMS (99 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Charng-Sheng TSAI, et al. Antibody drug conjugates. Patent. WO2023125530

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0767 mL	10.3834 mL	20.7667 mL	51.9168 mL
	5 mM	0.4153 mL	2.0767 mL	4.1533 mL	10.3834 mL
	10 mM	0.2077 mL	1.0383 mL	2.0767 mL	5.1917 mL
	15 mM	0.1384 mL	0.6922 mL	1.3844 mL	3.4611 mL
	20 mM	0.1038 mL	0.5192 mL	1.0383 mL	2.5958 mL
	25 mM	0.0831 mL	0.4153 mL	0.8307 mL	2.0767 mL
	30 mM	0.0692 mL	0.3461 mL	0.6922 mL	1.7306 mL
	40 mM	0.0519 mL	0.2596 mL	0.5192 mL	1.2979 mL
	50 mM	0.0415 mL	0.2077 mL	0.4153 mL	1.0383 mL
	60 mM	0.0346 mL	0.1731 mL	0.3461 mL	0.8653 mL
	80 mM	0.0260 mL	0.1298 mL	0.2596 mL	0.6490 mL
	100 mM	0.0208 mL	0.1038 mL	0.2077 mL	0.5192 mL