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  4. Rhamnus formosana Matsum.
  5. Frangulin B

Frangulin B, a natural compound that can be isolated from Rhamnus formosana, is an antagonist of collagen-induced platelet aggregation and adhesion.

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Frangulin B

Frangulin B Chemische Struktur

CAS. Nr. : 14101-04-3

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Beschreibung

Frangulin B, a natural compound that can be isolated from Rhamnus formosana, is an antagonist of collagen-induced platelet aggregation and adhesion[1].

Cellular Effect
Cell Line Type Value Description References
HL-60 IC50
15.7 μM
Compound: 2
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
[PMID: 20561793]
KB ED50
2.49 μg/mL
Compound: 6
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
10.1021/np50085a021
KB IC50
2.1 μM
Compound: 2
Cytotoxicity against human KB cells after 72 hrs by MTT assay
Cytotoxicity against human KB cells after 72 hrs by MTT assay
[PMID: 20561793]
MDA-MB-231 IC50
> 20 μM
Compound: 2
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay
[PMID: 20561793]
PLC-PRF-5 ED50
0.8 μg/mL
Compound: 6
Cytotoxicity against human PLC/PRF/5 cells
Cytotoxicity against human PLC/PRF/5 cells
10.1021/np50085a021
Molekulargewicht

402.35

Formel

C20H18O9

CAS. Nr.
SMILES

OC1=C2C(C(C(C=C(C)C=C3O)=C3C2=O)=O)=CC(O[C@@H]4OC[C@](O)(CO)[C@H]4O)=C1

Structure Classification
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation
Verweise
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  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Frangulin B
Art. -Nr.:
HY-N7316
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