Ganoderiol F

Cat. No.: HY-N3924 Purity: 99.85%: Data Sheet
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Ganoderiol F, a tetracyclic triterpene, is isolated from Ganoderma amboinense and found to induce senescence of cancer cell lines.

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Ganoderiol F 화학구조

CAS No. : 114567-47-4

사이즈	재고	수량
1 mg	해외재고보유	Estimated Time of Arrival: December 31
5 mg	견적 받기
10 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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Based on 1 Customer Validation

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순도&문서
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제품 설명

Ganoderiol F, a tetracyclic triterpene, is isolated from Ganoderma amboinense and found to induce senescence of cancer cell lines^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF S-180	IC₅₀	7.1 μg/mL Compound: 15	Cytotoxicity against mouse S180 cells Cytotoxicity against mouse S180 cells	[PMID: 23092389]
HEK293	EC₅₀	5 μM Compound: 14	Agonist activity at full length mouse FXR/RXRalpha expressed in human HEK293 cells assessed as induction of transcriptional activity after 18 hrs by dual luciferase reporter gene assay Agonist activity at full length mouse FXR/RXRalpha expressed in human HEK293 cells assessed as induction of transcriptional activity after 18 hrs by dual luciferase reporter gene assay	[PMID: 22014750]
HeLa	IC₅₀	5 μM Compound: 15	Cytotoxicity against human HeLa cells Cytotoxicity against human HeLa cells	[PMID: 23092389]
Hep 3B2	IC₅₀	25.3 μM Compound: 15	Cytotoxicity against human Hep3B cells Cytotoxicity against human Hep3B cells	[PMID: 23092389]
HepG2	IC₅₀	17 μM Compound: 15	Cytotoxicity against human HepG2 cells Cytotoxicity against human HepG2 cells	[PMID: 23092389]
HepG2	IC₅₀	20.7 μM Compound: 2	Anticancer activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay Anticancer activity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 24974349]
Huh-7	IC₅₀	8.5 μM Compound: 15	Cytotoxicity against human HuH7 cells Cytotoxicity against human HuH7 cells	[PMID: 23092389]
K562	IC₅₀	4 μM Compound: 15	Cytotoxicity against human K562 cells Cytotoxicity against human K562 cells	[PMID: 23092389]
K562	IC₅₀	54.9 μM Compound: 22	Cytotoxicity against human K562 cells by MTT method Cytotoxicity against human K562 cells by MTT method	[PMID: 26287401]
PC-3	IC₅₀	79.5 μM Compound: 22	Cytotoxicity against human PC3 cells by MTT method Cytotoxicity against human PC3 cells by MTT method	[PMID: 26287401]
RAW264.7	IC₅₀	36 μM Compound: 7	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production by Griess reaction method Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production by Griess reaction method	[PMID: 23357630]
T47D	IC₅₀	3 μg/mL Compound: 15	Cytotoxicity against human T47D cells Cytotoxicity against human T47D cells	[PMID: 23092389]

분자량

454.68

화학식

C₃₀H₄₆O₃

CAS No.

114567-47-4

Appearance

Solid

Color

White to off-white

SMILES

C[C@]1(CC[C@]2([H])[C@H](C)CC/C=C(CO)/CO)C(C3=CC[C@@]12C)=CC[C@](C(C)4C)([H])[C@@]3(CCC4=O)C

Structure Classification

Initial Source

Microorganisms

Ganoderma amboinense

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

순도&문서

Purity: 99.85%

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Data Sheet (265 KB) SDS (252 KB)

COA (248 KB) HNMR (85 KB) CNMR (94 KB) RP-HPLC (114 KB)

Handling Instructions (2659 KB)

References

[1]. Chang UM, et al. Ganoderiol F, a ganoderma triterpene, induces senescence in hepatoma HepG2 cells. Life Sci. 2006;79(12):1129-1139. [Content Brief]

Ganoderiol F Related Classifications

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ganoderiol F114567-47-4OthersInhibitorinhibitorinhibit

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Ganoderiol F

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Ganoderiol F Related Classifications

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