2. GPCR/G Protein
  3. GCGR GLP Receptor
  4. GIP/GLP-1 dual receptor agonist-1

GIP/GLP-1 dual receptor agonist-1 is a GIP/GLP-1 dual receptor agonist. GIP/GLP-1 dual receptor agonist-1 is used in the research of metabolic disorders and fatty liver diseases, including non-alcoholic steatohepatitis (NASH) and non-alcoholic fatty liver disease (NAFLD).

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GIP/GLP-1 dual receptor agonist-1

GIP/GLP-1 dual receptor agonist-1 Estructura química

No. CAS : 2807481-02-1

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GIP/GLP-1 dual receptor agonist-1 Related Antibodies

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Descripciòn

GIP/GLP-1 dual receptor agonist-1 is a GIP/GLP-1 dual receptor agonist. GIP/GLP-1 dual receptor agonist-1 is used in the research of metabolic disorders and fatty liver diseases, including non-alcoholic steatohepatitis (NASH) and non-alcoholic fatty liver disease (NAFLD)[1].

In Vitro

GIP/GLP-1 dual receptor agonist-1 acts as a dual binder for human GLP-1 and GIP receptors, with IC50 values of 105 nM (GLP-1 receptor) and 153 nM (GIP receptor) in the absence of HSA, and reduced binding affinity in the presence of 2% HSA[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

GIP/GLP-1 dual receptor agonist-1 Related Antibodies
Parmacokinetics
Species Dose Route T1/2
Monkey[1] 0.2 mg/kg s.c. 118 h
Peso molecular

4849.42

Fòrmula

C224H349N48O69P
No. CAS
Sequence

Tyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Aib}-Leu-Asp-Lys-Ile-Ala-Gln-{Lys(AEEA-AEEA-γGlu-C19 phosphoric acid)}-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
Sequence Shortening

Y-{Aib}-EGTFTSDYSI-{Aib}-LDKIAQ-{Lys(AEEA-AEEA-γGlu-C19 phosphoric acid)}-AFVQWLIAGGPSSGAPPPS-NH2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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GIP/GLP-1 dual receptor agonist-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GIP/GLP-1 dual receptor agonist-12807481-02-1GCGRGLP ReceptorGlucagon ReceptorGIP/GLP-1 dual receptor agonistnon-alcoholic steatohepatitis (NASH)non-alcoholic fatty liver disease (NAFLD)
Inhibitorinhibitorinhibit

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Nombre del producto:
GIP/GLP-1 dual receptor agonist-1
Cat. No.:
HY-153476
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