GLP-1 Receptor
GLP-1 receptor (GLP-1R) is a class B Gs-coupled GPCR activated by the incretin hormone glucagon-like peptide-1. Expressed on pancreatic beta cells, it potentiates glucose-dependent insulin secretion, suppresses glucagon release, slows gastric emptying and promotes satiety through central actions. Because these effects preserve euglycemia, GLP-1R agonists such as exenatide, liraglutide and semaglutide are cornerstones of type 2 diabetes therapy and have produced major weight loss in obesity indications. The receptor is also present in heart, kidney and neurons, and GLP-1R signaling is being investigated for neuroprotection and cardiovascular benefit. Recombinant GLP-1R is used for agonist screening and binding studies.
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GLP-1 Receptor Recombinant Proteins (9)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
