Glu-Glu (Synonyms: H-Glu-Glu-OH; Glutamyl-glutamic acid)

Name: Glu-Glu
Brand: MedChemExpress
SKU: HY-W016012
Rating: 4.5 (0 reviews)

Cat. No.: HY-W016012 Pureté: 98.0%: Fiche technique
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Glu-Glu is a glutamic acid derivative containing amino and carboxyl groups. Glu-Glu is an analogs of acidic tripeptide and can contribute to calcium absorption.

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Synthèse de peptides personnalisée

Glu-Glu Chemical Structure

CAS No. : 3929-61-1

Size	Stock	Quantité
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	En stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	En stock	Estimated Time of Arrival: December 31
Solid
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
250 mg	En stock	Estimated Time of Arrival: December 31
1 g	En stock	Estimated Time of Arrival: December 31
5 g	En stock	Estimated Time of Arrival: December 31
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50 g	Obtenir un devis

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Description

Glu-Glu is a glutamic acid derivative containing amino and carboxyl groups. Glu-Glu is an analogs of acidic tripeptide and can contribute to calcium absorption^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
MDCK	EC₅₀	1 2 Compound: 18	Activation of human PEPT1 expressed in MDCK cells Activation of human PEPT1 expressed in MDCK cells	[PMID: 16759105]
MDCK	EC₅₀	1 2 Compound: 18	Activation of human PEPT1 expressed in MDCK cells Activation of human PEPT1 expressed in MDCK cells	[PMID: 16759105]
MDCK	IC₅₀	0.62 2 Compound: 18	Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells	[PMID: 16759105]
MDCK	IC₅₀	0.62 2 Compound: 18	Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells	[PMID: 16759105]

In Vitro

Glu-Glu (5-10 mM in form of VSEE) improves the calcium uptake in Caco-2 cell monolayer model^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Masse moléculaire

276.24

Formule

C₁₀H₁₆N₂O₇

CAS No.

3929-61-1

Appearance

Solid

Color

White to off-white

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvant et solubilité

In Vitro:

H₂O : 5 mg/mL (18.10 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.6200 mL	18.1002 mL	36.2004 mL
5 mM	0.7240 mL	3.6200 mL	7.2401 mL
10 mM	0.3620 mL	1.8100 mL	3.6200 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Calculateur de molarité
Calculateur de dilution

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

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Working solution concentration: mg/mL

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Pureté et documentation

Purity: 98.0%

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Fiche technique (270 KB) SDS (393 KB)

COA (245 KB) HNMR (243 KB) MS (67 KB)

Instruction de manipulation (2659 KB)

Références

[1]. Guo D, et, al. Duck Egg White-Derived Peptide VSEE (Val-Ser-Glu-Glu) Regulates Bone and Lipid Metabolisms by Wnt/β-Catenin Signaling Pathway and Intestinal Microbiota. Mol Nutr Food Res. 2019 Dec;63(24):e1900525. [Content Brief]

[2]. Tamura M, et, al. The Relationship between Taste and Primary Structure of "Delicious Peptide" (Lys-Gly-Asp-Glu-Glu-Ser-Leu-Ala t) from Beef Soup. Agric. Bioi. Chem. 1989 Jul 6;52(2):319-25.

[3]. Hou T, et al. A pivotal peptide (Val-Ser-Glu-Glu) from duck egg white promotes calcium uptake and structure-activity relationship study[J]. Journal of functional foods, 2018, 48: 448-456.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.6200 mL	18.1002 mL	36.2004 mL	90.5010 mL
	5 mM	0.7240 mL	3.6200 mL	7.2401 mL	18.1002 mL
	10 mM	0.3620 mL	1.8100 mL	3.6200 mL	9.0501 mL
	15 mM	0.2413 mL	1.2067 mL	2.4134 mL	6.0334 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Glu-Glu Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glu-Glu3929-61-1H-Glu-Glu-OH Glutamyl-glutamic acidAmino Acid Derivativesglutamic acid derivativeaminocarboxylcalcium absorptionacidic tripeptideInhibitorinhibitorinhibit

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Glu-Glu (Synonyms: H-Glu-Glu-OH; Glutamyl-glutamic acid)

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Glu-Glu Related Antibodies

Recommandations en vedette

•Related Small Molecules:

•Related Proteins:

Activité biologique

Pureté et documentation

Références

Avis client

Glu-Glu Related Antibodies

Calculateur de molarité

Calculateur de dilution

Complete Stock Solution Preparation Table

Glu-Glu Related Classifications

Keywords:

Vos produits récemment consultés:

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SAFETY DATA SHEET (SDS)

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