2. PROTAC Immunology/Inflammation
  3. Molecular Glues IKZF Family
  4. IKZF2-degrader 1

IKZF2-degrader 1 (Compound 31) is a IKZF2 molecular glue degrader, with an DC50 of 0.5 nM. IKZF2-degrader 1 has minimal CK1α degradation activity relatively (DC50: 210 nM). IKZF2-degrader 1 can be used for research of IKZF2-dependent cancers.

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IKZF2-degrader 1

IKZF2-degrader 1 Estructura química

No. CAS : 2983840-43-1

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IKZF2-degrader 1 Related Antibodies

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Descripciòn

IKZF2-degrader 1 (Compound 31) is a IKZF2 molecular glue degrader, with an DC50 of 0.5 nM. IKZF2-degrader 1 has minimal CK1α degradation activity relatively (DC50: 210 nM). IKZF2-degrader 1 can be used for research of IKZF2-dependent cancers[1].

IC50 & Target[1]

IZKF2

0.5 nM (DC50)

Peso molecular

519.57

Fòrmula

C27H30FN7O3
No. CAS
SMILES

CC(C)NC1=NNC2=C(CN3CCCC3)C=C(C4=C(F)C(CN(C5CCC(NC5=O)=O)C6=O)=C6C=C4)N=C21
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

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Referencias
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IKZF2-degrader 1 Related Classifications

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Keywords:

IKZF2-degrader 12983840-43-1Molecular GluesIKZF FamilyIkaros zinc finger protein familyIKZF2 degradationcancerInhibitorinhibitorinhibit

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Nombre del producto:
IKZF2-degrader 1
Cat. No.:
HY-172882
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