2. Protein Tyrosine Kinase/RTK
  3. c-Met/HGFR
  4. JNJ-38877605-d1

JNJ-38877605-d1 (compound DO-2) is a highly selective MNNG HOS transforming (MET) inhibitor. JNJ-38877605-d1 is thought to diminish the formation of the Aldehyde Oxidase 1 inactive metabolite M3.

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JNJ-38877605-d<sub>1</sub>

JNJ-38877605-d1 화학구조

CAS No. : 1936472-36-4

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Other Forms of JNJ-38877605-d1:

JNJ-38877605-d1 Related Antibodies

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제품 설명

JNJ-38877605-d1 (compound DO-2) is a highly selective MNNG HOS transforming (MET) inhibitor. JNJ-38877605-d1 is thought to diminish the formation of the Aldehyde Oxidase 1 inactive metabolite M3[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Cellular Effect
Cell Line Type Value Description References
EBC-1 IC50
17 nM
Compound: 54
Antiproliferative activity against human EBC-1 cells assessed as inhibition of cell growth
Antiproliferative activity against human EBC-1 cells assessed as inhibition of cell growth
[PMID: 37262349]
MKN-45 IC50
25 nM
Compound: 54
Antiproliferative activity against human MKN-45 cells assessed as inhibition of cell growth
Antiproliferative activity against human MKN-45 cells assessed as inhibition of cell growth
[PMID: 37262349]
분자량

378.36

화학식

C19H12DF2N7
CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

FC(C1=CC=C(N=C([2H])C=C2)C2=C1)(F)C3=NN=C4N3N=C(C5=CN(C)N=C5)C=C4
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
순도&문서
References
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JNJ-38877605-d1 Related Classifications

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  • 농도 희석 계산기

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JNJ-38877605-d11936472-36-4c-Met/HGFRdeuteratedisotopehuman plasmaInhibitorinhibitorinhibit

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상품명:
JNJ-38877605-d1
Cat. No.:
HY-50683S
수량:
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