Mal-VC-PAB-PNP-CDN-A 

Mal-VC-PAB-PNP-CDN-A is a drug-Linker conjugates for ADC^[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1300.13

C₅₁H₆₇N₁₇O₂₀P₂

2640880-35-7

CC(C)[C@H](NC(CCCCCN1C(C=CC1=O)=O)=O)C(N[C@H](C(NC(C=C2)=CC=C2COC(NCC[C@@H]([C@@H](O3)[C@@H]4N5C=NC6=C5N=C(N)NC6=O)[C@H](O4)COP(O[C@H]7[C@@H](O)[C@H](N(C=N8)C9=C8C(N)=NC=N9)O[C@@H]7COP3(O)=O)(O)=O)=O)=O)CCCNC(N)=O)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Chen, Zhijian, et al. ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY. Patent. US20210015941A1.

  [2]. Wang Y, et al. Development of applicable thiol-linked antibody-drug conjugates with improved stability and therapeutic index. Drug Deliv. 2022 Dec;29(1):754-766.  [Content Brief]