2. Academic Validation
  3. Vasoconstrictor activity of 8-O-acetylharpagide from Ajuga reptans

Vasoconstrictor activity of 8-O-acetylharpagide from Ajuga reptans

  • J Nat Prod. 1992 Aug;55(8):1145-8. doi: 10.1021/np50086a019.
M C Breschi 1,  E Martinotti,  S Catalano,  G Flamini,  I Morelli,  A M Pagni
Affiliations

Affiliation

  • 1 Istituto Policattedra di Discipline Biologiche, Facoltà di Farmacia, Università di Pisa, Italy.
PMID: 1431938 DOI: 10.1021/np50086a019
Abstract

The traditional therapeutic indications for the use of Ajuga reptans (Labiatae) have been investigated. The H2O-soluble part of a crude and partially purified MeOH extract and two isolated Iridoids (8-O-acetylharpagide and harpagide), were tested for a biological activity on isolated smooth muscle preparations from guinea pig.

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