2. Academic Validation
  3. Antioxidant activity of butane type lignans, secoisolariciresinol, dihydroguaiaretic acid, and 7,7'-oxodihydroguaiaretic acid

Antioxidant activity of butane type lignans, secoisolariciresinol, dihydroguaiaretic acid, and 7,7'-oxodihydroguaiaretic acid

  • Biosci Biotechnol Biochem. 2008 Nov;72(11):2981-6. doi: 10.1271/bbb.80461.
Satoshi Yamauchi 1,  Toshiya Masuda,  Takuya Sugahara,  Yuya Kawaguchi,  Maya Ohuchi,  Tatsushi Someya,  Jun Akiyama,  Shiori Tominaga,  Manami Yamawaki,  Taro Kishida,  Koichi Akiyama,  Masafumi Maruyama
Affiliations

Affiliation

  • 1 Faculty of Agriculture, Ehime University, Japan.
PMID: 18997397 DOI: 10.1271/bbb.80461
Abstract

The antioxidant activity of butane-type Lignans was evaluated. Secoisolariciresinol (SECO) and dihydroguaiaretic acid (DGA) showed higher radical scavenging activity than that of 7,7'-dioxodihydroguaiaretic acid (ODGA). SECO and DGA inhibited the oxidation of unsaturated fatty acid. Both enantiomers of DGA were also Lipoxygenase inhibitors, but neither enantiomer of SECO inhibited the Lipoxygenase activity.

Figures
Products