2. Academic Validation
  3. Antiviral Effects of Polyphenols from Marine Algae

Antiviral Effects of Polyphenols from Marine Algae

  • Biomedicines. 2021 Feb 17;9(2):200. doi: 10.3390/biomedicines9020200.
Natalya N Besednova 1,  Boris G Andryukov 1 2,  Tatyana S Zaporozhets 1,  Sergey P Kryzhanovsky 3,  Ludmila N Fedyanina 2,  Tatyana A Kuznetsova 1,  Tatyana N Zvyagintseva 4,  Mikhail Yu Shchelkanov 1 2 5 6
Affiliations

Affiliations

  • 1 G.P. Somov Institute of Epidemiology and Microbiology, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, 690087 Vladivostok, Russia.
  • 2 School of Biomedicine, Far Eastern Federal University (FEFU), 690091 Vladivostok, Russia.
  • 3 Medical Association of the Far Eastern Branch of the Russian Academy of Sciences, 690022 Vladivostok, Russia.
  • 4 Elyakov Pacific Institute of Bioorganic Chemistry, FEB RAS, 690022 Vladivostok, Russia.
  • 5 Federal Scientific Center of the Eastern Asia Terrestrial Biodiversity, Far Eastern Branch of Russian Academy of Sciences, 690091 Vladivostok, Russia.
  • 6 National Scientific Center of Marine Biology, Far Eastern Branch of Russian Academy of Sciences, 690091 Vladivostok, Russia.
PMID: 33671278 DOI: 10.3390/biomedicines9020200
Abstract

The disease-preventive and medicinal properties of plant polyphenolic compounds have long been known. As active ingredients, they are used to prevent and treat many noncommunicable diseases. In recent decades, marine macroalgae have attracted the attention of biotechnologists and pharmacologists as a promising and almost inexhaustible source of Polyphenols. This heterogeneous group of compounds contains many biopolymers with unique structure and biological properties that exhibit high anti-infective activity. In the present review, the authors focus on the Antiviral potential of polyphenolic compounds (phlorotannins) from Marine algae and consider the mechanisms of their action as well as other biological properties of these compounds that have effects on the progress and outcome of viral infections. Effective nutraceuticals, to be potentially developed on the basis of algal Polyphenols, can also be used in the complex therapy of viral diseases. It is necessary to extend in vivo studies on laboratory Animals, which subsequently will allow proceeding to clinical tests. Polyphenolic compounds have a great potential as active ingredients to be used for the creation of new Antiviral pharmaceutical substances.

Keywords

anti-viral activity; antioxidants; flavonoids; marine algae; mechanism of action; polyphenols.

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