2. Academic Validation
  3. Dual blocking of PI3K and mTOR signaling by DHW-221, a novel benzimidazole derivative, exerts antitumor activity in human non-small cell lung cancer

Dual blocking of PI3K and mTOR signaling by DHW-221, a novel benzimidazole derivative, exerts antitumor activity in human non-small cell lung cancer

  • Clin Transl Med. 2021 Sep;11(9):e514. doi: 10.1002/ctm2.514.
Xiaochun Qin 1,  Mingyue Liu 1,  Yuting Wu 1,  Shu Wang 1,  Siheng Lian 1,  Hui Jia 2,  Qiong Wu 2,  Huaiwei Ding 3,  Qingchun Zhao 1 2
Affiliations

Affiliations

  • 1 Department of Life Science and Biochemistry, Shenyang Pharmaceutical University, Shenyang, China.
  • 2 Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang, China.
  • 3 Key Laboratory of Structure-Based Drug Design and Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, China.
PMID: 34586727 DOI: 10.1002/ctm2.514
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