2. Academic Validation
  3. Guar (Cyamopsis tetragonoloba L.) plant gum: From biological applications to advanced nanomedicine

Guar (Cyamopsis tetragonoloba L.) plant gum: From biological applications to advanced nanomedicine

  • Int J Biol Macromol. 2021 Dec 15;193(Pt B):1972-1985. doi: 10.1016/j.ijbiomac.2021.11.028.
Maryam Dehghani Soltani 1,  Heidar Meftahizadeh 2,  Mahmood Barani 3,  Abbas Rahdar 4,  Seyedeh Maryam Hosseinikhah 5,  Mehrnaz Hatami 6,  Mansour Ghorbanpour 7
Affiliations

Affiliations

  • 1 Department of Chemistry, Yazd University, Yazd 8915818411, Iran.
  • 2 Department of Horticultural Sciences, Faculty of Agriculture & Natural Resources, Ardakan University, P.O. Box 184, Ardakan, Iran. Electronic address: [email protected].
  • 3 Medical Mycology and Bacteriology Research Center, Kerman University of Medical Sciences, Kerman 7616913555, Iran.
  • 4 Department of Physics, University of Zabol, Zabol, P. O. Box. 98613-35856, Iran.
  • 5 Nanotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
  • 6 Department of Medicinal Plants, Faculty of Agriculture and Natural Resources, Arak University, Arak 38156-8-8349, Iran.
  • 7 Department of Medicinal Plants, Faculty of Agriculture and Natural Resources, Arak University, Arak 38156-8-8349, Iran. Electronic address: [email protected].
PMID: 34748787 DOI: 10.1016/j.ijbiomac.2021.11.028
Abstract

Natural Polymers are an efficient class of eco-friendly and biodegradable Polymers, because they are readily available, come from natural sources, inexpensive and can be chemically modified with the correct reagents. Guar gum (GG) is a natural polymer with great potential to be used in pharmaceutical formulations due to its unique composition and lack of toxicity. GG can be designed to suit the needs of the biological and medical engineering sectors. In the development of innovative drug delivery systems, GG is commonly utilized as a rate-controlling excipient. In this review, different properties of GG including chemical composition, extraction methods and its usefulness in diabetes, Cholesterol lowering, weight control, tablet formulations as well as its food application were discussed. The Other purpose of this study is to evaluate potential use of GG and its derivatives for advanced nanomedicine such as drug delivery, tissue engineering and nanosensing. It should be noted that some applicable patents in medical area have also been included in the rest of this survey to extend knowledge about guar gum and its polymeric nature.

Keywords

Galactomannan; Guar gum; Nanomedicine; Natural polymer; Natural polysaccharides.

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