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  4. Methyl 5-hydroxy-1H-indole-3-carboxylate

Methyl 5-hydroxy-1H-indole-3-carboxylate 

製品番号: HY-W064677 純度: 98.75%
COA 取扱説明書 Technical Support

Methyl 5-hydroxy-1H-indole-3-carboxylate is a marine natural product with isocitrate lyase inhibitory activity. Methyl 5-hydroxy-1H-indole-3-carboxylate is found in Hyrtios erectus. Methyl 5-hydroxy-1H-indole-3-carboxylate can be used to study its interaction with specific biological targets.

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Methyl 5-hydroxy-1H-indole-3-carboxylate

Methyl 5-hydroxy-1H-indole-3-carboxylate 構造式

CAS 番号 : 112332-96-4

容量 価格(税別) 在庫状況 数量
1 mg $230 在庫あり
2 mg $345 在庫あり
5 mg $538 在庫あり
10 mg $790 在庫あり
25 mg $1185 在庫あり
50 mg $1659 在庫あり
100 mg   お問い合わせ  
200 mg   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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製品説明

Methyl 5-hydroxy-1H-indole-3-carboxylate is a marine natural product with isocitrate lyase inhibitory activity. Methyl 5-hydroxy-1H-indole-3-carboxylate is found in Hyrtios erectus. Methyl 5-hydroxy-1H-indole-3-carboxylate can be used to study its interaction with specific biological targets[1].

Cellular Effect
Cell Line Type Value Description References
L5178Y IC50
0.052 μM
Compound: 19
Anticancer activity against mouse L5178Y assessed as cell growth inhibition by [3H]-thymidine assay
Anticancer activity against mouse L5178Y assessed as cell growth inhibition by [3H]-thymidine assay
[PMID: 33940466]
分子量

191.18

分子式

C10H9NO3

CAS 番号
Appearance

Powder

Color

Light brown to brown

SMILES

COC(C1=CNC2=C1C=C(O)C=C2)=O

Structure Classification
Initial Source

Hyrtios sp.

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

DMSO : 50 mg/mL (261.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2307 mL 26.1534 mL 52.3067 mL
5 mM 1.0461 mL 5.2307 mL 10.4613 mL
10 mM 0.5231 mL 2.6153 mL 5.2307 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始)

C1

×
体積 (開始)

V1

=
濃度 (終了)

C2

×
体積 (終了)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.2307 mL 26.1534 mL 52.3067 mL 130.7668 mL
5 mM 1.0461 mL 5.2307 mL 10.4613 mL 26.1534 mL
10 mM 0.5231 mL 2.6153 mL 5.2307 mL 13.0767 mL
15 mM 0.3487 mL 1.7436 mL 3.4871 mL 8.7178 mL
20 mM 0.2615 mL 1.3077 mL 2.6153 mL 6.5383 mL
25 mM 0.2092 mL 1.0461 mL 2.0923 mL 5.2307 mL
30 mM 0.1744 mL 0.8718 mL 1.7436 mL 4.3589 mL
40 mM 0.1308 mL 0.6538 mL 1.3077 mL 3.2692 mL
50 mM 0.1046 mL 0.5231 mL 1.0461 mL 2.6153 mL
60 mM 0.0872 mL 0.4359 mL 0.8718 mL 2.1794 mL
80 mM 0.0654 mL 0.3269 mL 0.6538 mL 1.6346 mL
100 mM 0.0523 mL 0.2615 mL 0.5231 mL 1.3077 mL
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Methyl 5-hydroxy-1H-indole-3-carboxylate Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます:C1V1 = C2V2

濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
Methyl 5-hydroxy-1H-indole-3-carboxylate
製品番号:
HY-W064677
数量:
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