1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. Calcium Channel
  3. MRS1845

MRS1845 

Cat. No.: HY-103310
Handling Instructions

MRS1845 is a Ca2+ channel blocker with relative specificity for store-operated calcium entry (SOCE) channels.

For research use only. We do not sell to patients.

MRS1845 Chemical Structure

MRS1845 Chemical Structure

CAS No. : 544478-19-5

Size Price Stock
5 mg USD 99 Get quote
10 mg USD 179 Get quote
50 mg USD 650 Get quote

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Description

MRS1845 is a Ca2+ channel blocker with relative specificity for store-operated calcium entry (SOCE) channels[1].

IC50 & Target

Ca2+ channel[1]

Molecular Weight

398.41

Formula

C₂₁H₂₂N₂O₆

CAS No.

544478-19-5

SMILES

O=C(C1=C(C)N(CC#C)C(C)=C(C(OC)=O)C1C2=CC=CC([N+]([O-])=O)=C2)OCC

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : ≥ 125 mg/mL (313.75 mM)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5100 mL 12.5499 mL 25.0998 mL
5 mM 0.5020 mL 2.5100 mL 5.0200 mL
10 mM 0.2510 mL 1.2550 mL 2.5100 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (5.22 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.22 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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  • Molarity Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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MRS1845
Cat. No.:
HY-103310
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