2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. Mu opioid receptor antagonist 1

Mu opioid receptor antagonist 1 (compound 19) is a selective and orally active μ opioid receptor (MOR) ligand with an Ki value of 0.58 nM and an EC50 of 1.15 nM. Orally administrating with Mu opioid receptor antagonist 1 increases intestinal motility during morphine-induced constipation. Mu opioid receptor antagonist 1 can be used for researching opioid-induced constipation (OIC).

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Mu opioid receptor antagonist 1

Mu opioid receptor antagonist 1 Chemische Struktur

CAS. Nr. : 2767446-03-5

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Mu opioid receptor antagonist 1 Related Antibodies

Top Publications Citing Use of Products

Alle Opioid Receptor Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen
μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

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Beschreibung

Mu opioid receptor antagonist 1 (compound 19) is a selective and orally active μ opioid receptor (MOR) ligand with an Ki value of 0.58 nM and an EC50 of 1.15 nM. Orally administrating with Mu opioid receptor antagonist 1 increases intestinal motility during morphine-induced constipation. Mu opioid receptor antagonist 1 can be used for researching opioid-induced constipation (OIC)[1].

IC50 & Target

μ Opioid Receptor/MOR

 

Molekulargewicht

436.50

Formel

C24H28N4O4
CAS. Nr.
SMILES

O[C@]12[C@H]3CC4=C5[C@@]1(CCN3CC6CC6)[C@H]([C@@H](CC2)NC(C7=CN=CN7)=O)OC5=C(O)C=C4
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
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Mu opioid receptor antagonist 1 Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mu opioid receptor antagonist 12767446-03-5Mu opioid receptor antagonist1Mu opioid receptor antagonist-1Opioid ReceptorGI tractOpioid-inducedConstipationIntestinal motilityOrally activeInhibitorinhibitorinhibit

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