1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. Opioid Receptor
  4. μ Opioid Receptor/MOR Isoform

μ Opioid Receptor/MOR

 

μ Opioid Receptor/MOR Related Products (29):

Cat. No. Product Name Effect Purity
  • HY-N0164
    Matrine
    Agonist ≥98.0%
    Matrine (Matridin-15-one) is an alkaloid found in plants from the Sophora genus that can act as a kappa opioid receptor and u-receptor agonist.
  • HY-15122A
    Sinomenine hydrochloride
    Activator 99.88%
    Sinomenine hydrochloride (Cucoline hydrochloride), an alkaloid extracted from Sinomenium acutum, is a blocker of the NF-κB activation.
  • HY-P0185
    Endomorphin 1
    Agonist 99.92%
    Endomorphin 1, a high affinity, highly selective agonist of the μ-opioid receptor (Ki: 1.11 nM), displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM.
  • HY-124754
    Navacaprant
    Inhibitor 99.71%
    Navacaprant (BTRX-335140) is a selective and orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively.
  • HY-P1335A
    CTAP TFA
    Antagonist 99.56%
    CTAP TFA is a potent, highly selective, and BBB penetrant μ opioid receptor antagonist, with an IC50 of 3.5 nM.
  • HY-P0185A
    Endomorphin 1 acetate
    Agonist 99.92%
    Endomorphin 1 acetate, a high affinity, highly selective agonist of the μ-opioid receptor (Ki: 1.11 nM), displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM.
  • HY-151811
    NAQ
    Agonist
    NAQ is a potent and selective μ opioid receptor partial agonist, with a Ki of 0.55 nM.
  • HY-114072
    J-113397
    Antagonist
    J-113397 is the first potent and selective nonpeptidyl ORL1 receptor antagonist (Ki: cloned human ORL1=1.8 nM) without any agonistic effects on other opioid receptors.
  • HY-P0244
    Dermorphin
    Agonist 98.06%
    Dermorphin is a natural heptapeptide μ-opioid receptor (MOR) agonist found in amphibian skin.
  • HY-N0923
    Corydaline
    Agonist 98.44%
    Corydaline ((+)-Corydaline), an isoquinoline alkaloid isolated from Corydalis yanhusuo, is an AChE inhibitor with an IC50 of 226 µM.
  • HY-P1329A
    CTOP TFA
    Antagonist 99.93%
    CTOP TFA is a potent and highly selective μ-opioid receptor antagonist.
  • HY-P1087
    Adrenorphin
    Agonist
    Adrenorphin is a opioid octapeptide, acting as a potent agonist of μ-opioid receptor, with Ki of 12 nM.
  • HY-P1866A
    β-Endorphin, equine TFA
    Agonist
    β-Endorphin, equine TFA is an endogenous opioid peptide, which binds at high affinity to both μ/δ opioid receptors.
  • HY-P1701
    Morphiceptin
    99.35%
    Morphiceptin is a potent and specific agonist for morphine (μ) receptors.
  • HY-107748
    5'-Guanidinonaltrindole hydrochloride
    Antagonist 98.65%
    5'-Guanidinonaltrindole (5'-GNTI) hydrochloride is a highly selective and potent κ-opioid receptor antagonist with a Ki of 0.18 nM for human κ-opioid receptor.
  • HY-N0398
    Sec-O-Glucosylhamaudol
    Inhibitor 99.89%
    Sec-O-Glucosylhamaudol is a natural compound extracted from Peucedanum japonicum Thunb, decreases levels of μ-opioid receptor, with analgesic effect.
  • HY-101011
    Naloxonazine dihydrochloride
    Antagonist
    Naloxonazine dihydrochloride is a specific μ-opioid receptor antagonist with an IC50 of 5.4 nM.
  • HY-141515
    BMS-986121
    Modulator 98.89%
    BMS-986121 is a positive allosteric modulator (PAM) of the μ opioid receptor extracted from patent WO2014107344.
  • HY-115066
    GSK1521498 free base
    Antagonist 98.55%
    GSK1521498 free base is a potent and selective μ-opioid receptor (MOR) antagonist.
  • HY-P1335
    CTAP
    Antagonist
    CTAP is a potent, highly selective, and BBB penetrant μ opioid receptor antagonist, with an IC50 of 3.5 nM.